Pravdivtsev, Andrey N. ; Buntkowsky, Gerd ; Duckett, Simon B. ; Koptyug, Igor V. ; Hövener, Jan‐Bernd (2023)
Parahydrogen‐Induced Polarization of Amino Acids.
In: Angewandte Chemie International Edition, 2021, 60 (44)
doi: 10.26083/tuprints-00024215
Artikel, Zweitveröffentlichung, Verlagsversion
Kurzbeschreibung (Abstract)
Nuclear magnetic resonance (NMR) has become a universal method for biochemical and biomedical studies, including metabolomics, proteomics, and magnetic resonance imaging (MRI). By increasing the signal of selected molecules, the hyperpolarization of nuclear spin has expanded the reach of NMR and MRI even further (e.g. hyperpolarized solid-state NMR and metabolic imaging in vivo). Parahydrogen (pH₂) offers a fast and cost-efficient way to achieve hyperpolarization, and the last decade has seen extensive advances, including the synthesis of new tracers, catalysts, and transfer methods. The portfolio of hyperpolarized molecules now includes amino acids, which are of great interest for many applications. Here, we provide an overview of the current literature and developments in the hyperpolarization of amino acids and peptides.
| Typ des Eintrags: | Artikel |
|---|---|
| Erschienen: | 2023 |
| Autor(en): | Pravdivtsev, Andrey N. ; Buntkowsky, Gerd ; Duckett, Simon B. ; Koptyug, Igor V. ; Hövener, Jan‐Bernd |
| Art des Eintrags: | Zweitveröffentlichung |
| Titel: | Parahydrogen‐Induced Polarization of Amino Acids |
| Sprache: | Englisch |
| Publikationsjahr: | 2023 |
| Ort: | Darmstadt |
| Publikationsdatum der Erstveröffentlichung: | 2021 |
| Verlag: | Wiley |
| Titel der Zeitschrift, Zeitung oder Schriftenreihe: | Angewandte Chemie International Edition |
| Jahrgang/Volume einer Zeitschrift: | 60 |
| (Heft-)Nummer: | 44 |
| DOI: | 10.26083/tuprints-00024215 |
| URL / URN: | https://tuprints.ulb.tu-darmstadt.de/24215 |
| Zugehörige Links: | |
| Herkunft: | Zweitveröffentlichungsservice |
| Kurzbeschreibung (Abstract): | Nuclear magnetic resonance (NMR) has become a universal method for biochemical and biomedical studies, including metabolomics, proteomics, and magnetic resonance imaging (MRI). By increasing the signal of selected molecules, the hyperpolarization of nuclear spin has expanded the reach of NMR and MRI even further (e.g. hyperpolarized solid-state NMR and metabolic imaging in vivo). Parahydrogen (pH₂) offers a fast and cost-efficient way to achieve hyperpolarization, and the last decade has seen extensive advances, including the synthesis of new tracers, catalysts, and transfer methods. The portfolio of hyperpolarized molecules now includes amino acids, which are of great interest for many applications. Here, we provide an overview of the current literature and developments in the hyperpolarization of amino acids and peptides. |
| Freie Schlagworte: | amino acids, catalysis, hydrogenation, hyperpolarization, parahydrogen |
| Status: | Verlagsversion |
| URN: | urn:nbn:de:tuda-tuprints-242159 |
| Sachgruppe der Dewey Dezimalklassifikatin (DDC): | 500 Naturwissenschaften und Mathematik > 530 Physik 500 Naturwissenschaften und Mathematik > 540 Chemie |
| Fachbereich(e)/-gebiet(e): | 07 Fachbereich Chemie 07 Fachbereich Chemie > Eduard Zintl-Institut > Fachgebiet Physikalische Chemie |
| Hinterlegungsdatum: | 13 Jul 2023 12:36 |
| Letzte Änderung: | 17 Jul 2023 06:13 |
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