Bögözi, Timea ; Popp, Jürgen ; Frosch, Torsten (2015)
Fiber-enhanced Raman multi-gas spectroscopy: what is the potential of its application to breath analysis?
In: Bioanalysis, 7 (3)
doi: 10.4155/bio.14.299
Artikel, Bibliographie
Kurzbeschreibung (Abstract)
The ancient Greek physicians were already aware that some diseases could be diagnosed from the characteristic odor of patients’ breath. For example – patients with liver failure present a fish-like smell, and a urine-like scent indicates renal failure [1]. The identification of breath compounds for noninvasive medical diagnosis has drawn increasing interest in recent years. Sniffer dogs were successfully trained for the identification of breath samples from lung cancer patients [2,3]. More than 100 volatile organic compounds (VOCs) have been identified in normal human breath, and efforts were made for better understanding of complex VOCs patterns that appear in exhaled breath during specific physiological and pathophysiological processes [1,4,5]. For unambitious disease diagnosis and better understanding of the biochemical pathways, a thorough identification and quantification of the disease markers is essential. The editorial aims to highlight the potential of fiber-enhanced Raman spectroscopy (FERS) as an innovative technique for fast and painless point-of-care (POC) diagnosis of diseases in exhaled human breath. After a short review of some well-established analytical techniques for breath diagnosis, FERS is introduced as novel tool and discussed on some application examples.
| Typ des Eintrags: | Artikel |
|---|---|
| Erschienen: | 2015 |
| Autor(en): | Bögözi, Timea ; Popp, Jürgen ; Frosch, Torsten |
| Art des Eintrags: | Bibliographie |
| Titel: | Fiber-enhanced Raman multi-gas spectroscopy: what is the potential of its application to breath analysis? |
| Sprache: | Englisch |
| Publikationsjahr: | 20 Februar 2015 |
| Verlag: | Future Science Ltd. |
| Titel der Zeitschrift, Zeitung oder Schriftenreihe: | Bioanalysis |
| Jahrgang/Volume einer Zeitschrift: | 7 |
| (Heft-)Nummer: | 3 |
| DOI: | 10.4155/bio.14.299 |
| Kurzbeschreibung (Abstract): | The ancient Greek physicians were already aware that some diseases could be diagnosed from the characteristic odor of patients’ breath. For example – patients with liver failure present a fish-like smell, and a urine-like scent indicates renal failure [1]. The identification of breath compounds for noninvasive medical diagnosis has drawn increasing interest in recent years. Sniffer dogs were successfully trained for the identification of breath samples from lung cancer patients [2,3]. More than 100 volatile organic compounds (VOCs) have been identified in normal human breath, and efforts were made for better understanding of complex VOCs patterns that appear in exhaled breath during specific physiological and pathophysiological processes [1,4,5]. For unambitious disease diagnosis and better understanding of the biochemical pathways, a thorough identification and quantification of the disease markers is essential. The editorial aims to highlight the potential of fiber-enhanced Raman spectroscopy (FERS) as an innovative technique for fast and painless point-of-care (POC) diagnosis of diseases in exhaled human breath. After a short review of some well-established analytical techniques for breath diagnosis, FERS is introduced as novel tool and discussed on some application examples. |
| Freie Schlagworte: | Fiber Enhanced Raman Spectroscopy FERS, Breath Analysis, Biomedical Spectroscopy, Gas Sensing, Multigas Sensing, Gas Analysis, hollow core photonic crystal fiber |
| Fachbereich(e)/-gebiet(e): | 18 Fachbereich Elektrotechnik und Informationstechnik 18 Fachbereich Elektrotechnik und Informationstechnik > Biophotonik-Medizintechnik |
| Hinterlegungsdatum: | 19 Jan 2024 10:09 |
| Letzte Änderung: | 25 Apr 2024 10:12 |
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