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Anzahl der Einträge: 26.

Porro, Alessandro ; Saponaro, Andrea ; Castelli, Roberta ; Introini, Bianca ; Hafez Alkotob, Anahita ; Ranjbari, Golnaz ; Enke, Uta ; Kusch, Jana ; Benndorf, Klaus ; Santoro, Bina ; DiFrancesco, Dario ; Thiel, Gerhard ; Moroni, Anna (2024)
A high affinity switch for cAMP in the HCN pacemaker channels.
In: Nature communications, 15 (1)
doi: 10.1038/s41467-024-45136-y
Artikel, Bibliographie

Krumbach, Jan H. ; Bauer, Daniel ; Sharifzadeh, Atiyeh Sadat ; Saponaro, Andrea ; Lautenschläger, Rene ; Lange, Kristina ; Rauh, Oliver ; DiFrancesco, Dario ; Moroni, Anna ; Thiel, Gerhard ; Hamacher, Kay (2023)
Alkali metal cations modulate the geometry of different binding sites in HCN4 selectivity filter for permeation or block.
In: The Journal of general physiology, 155 (10)
doi: 10.1085/jgp.202313364
Artikel, Bibliographie

Carvalho-de-Souza, Joao Luis ; Saponaro, Andrea ; Bassetto, C. A. Z. ; Rauh, Oliver ; Schroeder, Indra ; Franciolini, Fabio ; Catacuzzeno, Luigi ; Bezanilla, Francisco ; Thiel, Gerhard ; Moroni, Anna (2022)
Experimental challenges in ion channel research : uncovering basic principles of permeation and gating in potassium channels.
In: Advances in Physics: X, 7 (1)
doi: 10.1080/23746149.2021.1978317
Artikel, Bibliographie

Porro, Alessandro ; Saponaro, Andrea ; Gasparri, Federica ; Bauer, Daniel ; Gross, Christine ; Pisoni, Matteo ; Abbandonato, Gerardo ; Hamacher, Kay ; Santoro, Bina ; Thiel, Gerhard ; Moroni, Anna (2022)
The HCN domain couples voltage gating and cAMP response in hyperpolarization-activated cyclic nucleotide-gated channels.
In: eLife, 2019, 2019
doi: 10.26083/tuprints-00013344
Artikel, Zweitveröffentlichung, Verlagsversion

Saponaro, Andrea ; Cantini, Francesca ; Porro, Alessandro ; Bucchi, Annalisa ; DiFrancesco, Dario ; Maione, Vincenzo ; Donadoni, Chiara ; Introini, Bianca ; Mesirca, Pietro ; Mangoni, Matteo E. ; Thiel, Gerhard ; Banci, Lucia ; Santoro, Bina ; Moroni, Anna (2022)
A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels.
In: eLife, 2018, 2018
doi: 10.26083/tuprints-00013339
Artikel, Zweitveröffentlichung, Verlagsversion

Saponaro, Andrea ; Thiel, Gerhard ; Moroni, Anna (2021)
Structural and functional approaches to studying cAMP regulation of HCN channels.
In: Biochemical Society transactions
doi: 10.1042/BST20210290
Artikel, Bibliographie

Saponaro, Andrea ; Bauer, Daniel ; Giese, M. Hunter ; Swuec, Paolo ; Porro, Alessandro ; Gasparri, Federica ; Sharifzadeh, Atiyeh Sadat ; Chaves-Sanjuan, Antonio ; Alberio, Laura ; Parisi, Giacomo ; Cerutti, Gabriele ; Clarke, Oliver B. ; Hamacher, Kay ; Colecraft, Henry M. ; Mancia, Filippo ; Hendrickson, Wayne A. ; Siegelbaum, Steven A. ; DiFrancesco, Dario ; Bolognesi, Martino ; Thiel, Gerhard ; Santoro, Bina ; Moroni, Anna (2021)
Gating movements and ion permeation in HCN4 pacemaker channels.
In: Molecular cell, 81 (14)
doi: 10.1016/j.molcel.2021.05.033
Artikel, Bibliographie

Kukovetz, Kerri ; Hertel, Brigitte ; Schvarcz, Christopher R. ; Saponaro, Andrea ; Manthey, Mirja ; Burk, Ulrike ; Greiner, Timo ; Steward, Grieg F. ; Etten, James L. van ; Moroni, Anna ; Thiel, Gerhard ; Rauh, Oliver (2021)
A Functional K+ Channel from Tetraselmis Virus 1, a Member of the Mimiviridae.
In: Viruses, 2020, 12 (10)
doi: 10.26083/tuprints-00019251
Artikel, Zweitveröffentlichung, Verlagsversion

Kukovetz, Kerri ; Hertel, Brigitte ; Schvarcz, Christopher R. ; Saponaro, Andrea ; Manthey, Mirja ; Burk, Ulrike ; Greiner, Timo ; Steward, Grieg F. ; Etten, James L. van ; Moroni, Anna ; Thiel, Gerhard ; Rauh, Oliver (2020)
A Functional K+ Channel from Tetraselmis Virus 1, a Member of the Mimiviridae.
In: Viruses, 12 (10)
doi: 10.3390/v12101107
Artikel, Bibliographie

Porro, Alessandro ; Thiel, Gerhard ; Moroni, Anna ; Saponaro, Andrea (2020)
Cyclic AMP Regulation and Its Command in the Pacemaker Channel HCN4.
In: Frontiers in physiology, 11
doi: 10.3389/fphys.2020.00771
Artikel, Bibliographie

Introini, Bianca ; Saponaro, Andrea ; Bonucci, Alessio ; Rauh, Oliver ; Cantini, Francesca ; Banci, Lucia ; Thiel, Gerhard ; Moroni, Anna (2020)
Camp-Induced Conformational Changes in the C-Linker of HCN4.
In: Biophysical Journal, 118 (3)
doi: 10.1016/j.bpj.2019.11.2365
Artikel, Bibliographie

Laskowski, Michal ; Saponaro, Andrea ; Porro, Alessandro ; Zurbriggen, Matias ; Thiel, Gerhard ; Moroni, Anna (2020)
Lov-Nano as a New Tool for the Regulation of HCN Channels by Blue Light.
In: Biophysical Journal, 118 (3)
doi: 10.1016/j.bpj.2019.11.1558
Artikel, Bibliographie

Porro, Alessandro ; Gasparri, Federica ; Cona, Filippo ; Thiel, Gerhard ; Thei, Federico ; Santoro, Bina ; Saponaro, Andrea ; Moroni, Anna (2020)
The Role of HCN Channel Helices D and E in the Modulation of Camp Affinity.
In: Biophysical Journal, 118 (3)
doi: 10.1016/j.bpj.2019.11.2350
Artikel, Bibliographie

Porro, Alessandro ; Saponaro, Andrea ; Gasparri, Federica ; Bauer, Daniel ; Gross, Christine ; Pisoni, Matteo ; Abbandonato, Gerardo ; Hamacher, Kay ; Santoro, Bina ; Thiel, Gerhard ; Moroni, Anna (2019)
The HCN domain couples voltage gating and cAMP response in Hyperpolarization-activated Cyclic Nucleotide-gated channels.
In: eLife, 8
doi: 10.7554/eLife.49672
Artikel, Bibliographie

Introini, Bianca ; Saponaro, Andrea ; Bonucci, Alessio ; Rauh, Oliver ; Cantini, Francesca ; Banci, Lucia ; Thiel, Gerhard ; Moroni, Anna (2019)
Chimeric HCN Channels for Studying Camp-Induced Conformational Changes in the C-Linker.
In: Biophysical Journal, 116 (3)
doi: 10.1016/j.bpj.2018.11.1631
Artikel, Bibliographie

Saponaro, Andrea ; Cantini, Francesca ; Porro, Alessandro ; Bucchi, Annalisa ; DiFrancesco, Dario ; Maione, Vincenzo ; Laskowski, Michal ; Mesirca, Pietro ; Mangoni, Matteo ; Thiel, Gerhard ; Banci, Lucia ; Santoro, Bina ; Moroni, Anna (2019)
Developing Synthetic Peptides to Regulate Native HCN Channels.
In: Biophysical Journal, 116 (3)
doi: 10.1016/j.bpj.2018.11.1638
Artikel, Bibliographie

Moroni, Anna ; Porro, Alessandro ; Saponaro, Andrea ; Pisoni, Matteo ; Gasparri, Federica ; Abbandonato, Gerardo ; Thiel, Gerhard ; Santoro, Bina (2019)
The Role of HCN Domain in Channel Gating.
In: Biophysical Journal, 116 (3)
doi: 10.1016/j.bpj.2018.11.2146
Artikel, Bibliographie

Alberio, Laura ; Locarno, Andrea ; Saponaro, Andrea ; Romano, Edoardo ; Bercier, Valérie ; Albadri, Shahad ; Simeoni, Frederica ; Moleri, Silvia ; Pelucchi, Silvia ; Porro, Alessandro ; Marcello, Elena ; Barsotti, Noemi ; Kukovetz, Kerri ; Boender, Arjen J. ; Contestabile, Andrea ; Luo, Shizhen ; Moutal, Aubin ; Ji, Yingshi ; Romani, Giulia ; Beltrame, Monica ; Del Bene, Filippo ; Di Luca, Monica ; Khanna, Rajesh ; Colecraft, Henry M. ; Pasqualetti, Massimo ; Thiel, Gerhard ; Tonini, Raffaella ; Moroni, Anna (2018)
A light-gated potassium channel for sustained neuronal inhibition.
In: Nature methods, 15 (11)
Artikel, Bibliographie

Groß, Christine ; Saponaro, Andrea ; Santoro, Bina ; Moroni, Anna ; Thiel, Gerhard ; Hamacher, Kay (2018)
Mechanical transduction of cytoplasmic-to-transmembrane-domain movements in a hyperpolarization-activated cyclic nucleotide-gated cation channel.
In: The Journal of biological chemistry, 293 (33)
doi: 10.1074/jbc.RA118.002139
Artikel, Bibliographie

Saponaro, Andrea ; Cantini, Francesca ; Porro, Alessandro ; Bucchi, Annalisa ; DiFrancesco, Dario ; Maione, Vincenzo ; Donadoni, Chiara ; Introini, Bianca ; Mesirca, Pietro ; Mangoni, Matteo Elia ; Thiel, Gerhard ; Banci, Lucia ; Santoro, Bina ; Moroni, Anna (2018)
A synthetic peptide that prevents cAMP regulation in mammalian Hyperpolarization-activated Cyclic Nucleotide-regulated (HCN) channels.
In: eLife, 7
Artikel, Bibliographie

Saponaro, Andrea ; Porro, Alessandro ; Donadoni, Chiara ; Santoro, Bina ; Thiel, Gerhard ; Moroni, Anna (2018)
Assigning Function to the D and E Helices of HCN CNBD.
In: Biophysical journal, 114 (3)
Artikel, Bibliographie

Saponaro, Andrea ; Porro, Alessandro ; Chaves-Sanjuan, Antonio ; Nardini, Marco ; Rauh, Oliver ; Thiel, Gerhard ; Moroni, Anna (2017)
Fusicoccin Activates KAT1 Channels by Stabilizing their Interaction with 14-3-3- Proteins.
In: The Plant cell, 29 (10)
Artikel, Bibliographie

Saponaro, Andrea ; Porro, Alessandro ; Sanjuan, Antonio C. ; Donadoni, Chiara ; Nardini, Marco ; Thiel, Gerhard ; Moroni, Anna (2017)
Exploring New Pharmacological Perspectives of Fusicoccin, A Stabilizer of 14-3-3-Target Protein Complex.
In: Biophysical journal, 112 (3)
Artikel, Bibliographie

Weißgraeber, Stephanie ; Saponaro, Andrea ; Thiel, Gerhard ; Hamacher, Kay (2017)
A reduced mechanical model for cAMP-modulated gating in HCN channels.
In: Scientific reports, 7
Artikel, Bibliographie

Saponaro, Andrea ; Pauleta, Sofia R. ; Cantini, Francesca ; Matzapetakis, Manolis ; Hammann, Christian ; Donadoni, Chiara ; Hu, Lei ; Thiel, Gerhard ; Banci, Lucia ; Santoro, Bina ; Moroni, Anna (2014)
Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function.
In: Proceedings of the National Academy of Sciences of the United States of America, 11 (40)
Artikel, Bibliographie

Smeazzetto, Serena ; Saponaro, Andrea ; Young, Howard S. ; Moncelli, Maria Rosa ; Thiel, Gerhard (2013)
Structure-Function Relation of Phospholamban: Modulation of Channel Activity as a Potential Regulator of SERCA Activity.
In: PloS one, 8 (1)
Artikel, Bibliographie

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