Brust, M. ; Schäfer, C. ; Dörr, Roland ; Pan, L. ; Garcia, M. ; Arratia, P. E. ; Wagner, C. (2013)
Rheology of human blood plasma: Viscoelastic versus Newtonian behavior.
In: Physical Review Letters, 110
doi: 10.1103/PhysRevLett.110.078305
Article
Abstract
We investigate the rheological characteristics of human blood plasma in shear and elongational flows. While we can confirm a Newtonian behavior in shear flow within experimental resolution, we find a viscoelastic behavior of blood plasma in the pure extensional flow of a capillary break-up rheometer. The influence of the viscoelasticity of blood plasma on capillary blood flow is tested in a microfluidic device with a contraction-expansion geometry. Differential pressure measurements revealed that the plasma has a pronounced flow resistance compared to that of pure water. Supple- mentary measurements indicate that the viscoelasticity of the plasma might even lead to viscoelastic instabilities under certain conditions. Our findings show that the viscoelastic properties of plasma should not be ignored in future studies on blood flow.
| Item Type: | Article |
|---|---|
| Erschienen: | 2013 |
| Creators: | Brust, M. ; Schäfer, C. ; Dörr, Roland ; Pan, L. ; Garcia, M. ; Arratia, P. E. ; Wagner, C. |
| Type of entry: | Bibliographie |
| Title: | Rheology of human blood plasma: Viscoelastic versus Newtonian behavior |
| Language: | English |
| Date: | 15 February 2013 |
| Publisher: | American Physical Society |
| Journal or Publication Title: | Physical Review Letters |
| Volume of the journal: | 110 |
| DOI: | 10.1103/PhysRevLett.110.078305 |
| URL / URN: | https://journals.aps.org/prl/abstract/10.1103/PhysRevLett.11... |
| Abstract: | We investigate the rheological characteristics of human blood plasma in shear and elongational flows. While we can confirm a Newtonian behavior in shear flow within experimental resolution, we find a viscoelastic behavior of blood plasma in the pure extensional flow of a capillary break-up rheometer. The influence of the viscoelasticity of blood plasma on capillary blood flow is tested in a microfluidic device with a contraction-expansion geometry. Differential pressure measurements revealed that the plasma has a pronounced flow resistance compared to that of pure water. Supple- mentary measurements indicate that the viscoelasticity of the plasma might even lead to viscoelastic instabilities under certain conditions. Our findings show that the viscoelastic properties of plasma should not be ignored in future studies on blood flow. |
| Uncontrolled Keywords: | Blood, Blood plasma, Viscoelastic behavior, Newtonian Behavior, Rheology |
| Divisions: | 18 Department of Electrical Engineering and Information Technology 18 Department of Electrical Engineering and Information Technology > Institute for Electromechanical Design (dissolved 18.12.2018) 18 Department of Electrical Engineering and Information Technology > Microtechnology and Electromechanical Systems |
| Date Deposited: | 07 Nov 2017 08:42 |
| Last Modified: | 09 Mar 2022 08:39 |
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