Lu, J. ; Grass, P. ; Koeppl, H. (2011):
Computational identification of optimal multi target drug intervention strategies for combination theory.
p. 132, Zurich, Eighth International Workshop on Computational Systems Biology, WCSB 2011, June 6-8, 2011, Zurich, Switzerland, [Conference or Workshop Item]
Abstract
Combination drug intervention strategies offer the potential to tackle the problems of side effects and resistance mechanisms. We propose a methodology that incorporates robustness into the identified intervention strategy in order to counteract the inevitable variability in physiological settings. We show that in order to attain the goals in a robust manner, multiple nodes need to be inhibited
| Item Type: | Conference or Workshop Item |
|---|---|
| Erschienen: | 2011 |
| Creators: | Lu, J. ; Grass, P. ; Koeppl, H. |
| Title: | Computational identification of optimal multi target drug intervention strategies for combination theory |
| Language: | English |
| Abstract: | Combination drug intervention strategies offer the potential to tackle the problems of side effects and resistance mechanisms. We propose a methodology that incorporates robustness into the identified intervention strategy in order to counteract the inevitable variability in physiological settings. We show that in order to attain the goals in a robust manner, multiple nodes need to be inhibited |
| Place of Publication: | Zurich |
| Divisions: | 18 Department of Electrical Engineering and Information Technology 18 Department of Electrical Engineering and Information Technology > Institute for Telecommunications > Bioinspired Communication Systems 18 Department of Electrical Engineering and Information Technology > Institute for Telecommunications |
| Event Title: | Eighth International Workshop on Computational Systems Biology, WCSB 2011, June 6-8, 2011, Zurich, Switzerland |
| Date Deposited: | 04 Apr 2014 12:24 |
| URL / URN: | http://www.wcsb2011.ethz.ch/programme |
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