Berens, Christian ; Suess, Beatrix (2005)
Synthetic riboregulators - an alternative means to control gene expression.
In: Gene therapy and molecular biology, 9
Article, Bibliographie
Abstract
During the last years, the important role RNA plays for regulating gene expression in all organisms has become obvious. Consequently, several recent approaches aim to utilize the outstanding chemical properties of RNA in developing artificial RNA regulators for conditional gene expression systems. Rational design, in vitro selection and in vivo screening systems have been combined to create a versatile set of RNA based molecular switches. These tools rely on diverse mechanisms and exhibit activity in several organisms. In this review, we summarize recent developments in the application of synthetic riboswitches for gene regulation in vivo.
| Item Type: | Article |
|---|---|
| Erschienen: | 2005 |
| Creators: | Berens, Christian ; Suess, Beatrix |
| Type of entry: | Bibliographie |
| Title: | Synthetic riboregulators - an alternative means to control gene expression |
| Language: | English |
| Date: | 2005 |
| Journal or Publication Title: | Gene therapy and molecular biology |
| Volume of the journal: | 9 |
| Abstract: | During the last years, the important role RNA plays for regulating gene expression in all organisms has become obvious. Consequently, several recent approaches aim to utilize the outstanding chemical properties of RNA in developing artificial RNA regulators for conditional gene expression systems. Rational design, in vitro selection and in vivo screening systems have been combined to create a versatile set of RNA based molecular switches. These tools rely on diverse mechanisms and exhibit activity in several organisms. In this review, we summarize recent developments in the application of synthetic riboswitches for gene regulation in vivo. |
| Divisions: | 10 Department of Biology > Synthetic Genetic Circuits (2020 renamed "Synthetic RNA biology) 10 Department of Biology |
| Date Deposited: | 22 Feb 2012 12:42 |
| Last Modified: | 05 Mar 2013 09:59 |
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