TU Darmstadt / ULB / TUbiblio

Aptamers and riboswitches: perspectives in biotechnology.

Weigand, Julia E. and Suess, Beatrix (2009):
Aptamers and riboswitches: perspectives in biotechnology.
In: Applied microbiology and biotechnology, 85 (2), pp. 229-36. ISSN 1432-0614,
[Article]

Abstract

Aptamers are short, single stranded nucleic acids which bind a wide range of different ligands with extraordinary high binding affinity and specificity. The steadily increasing number of aptamers is accompanied by an expanding range of applications in biotechnology. We will describe new developments in the field including the use of aptamers for conditional gene regulation and as biosensors. In addition, we will discuss the potential of aptamers as tags to visualize RNA and protein distribution in living cells and as therapeutics. Furthermore, we will consider biotechnological applications of riboswitches for gene regulation and as drug target.

Item Type: Article
Erschienen: 2009
Creators: Weigand, Julia E. and Suess, Beatrix
Title: Aptamers and riboswitches: perspectives in biotechnology.
Language: English
Abstract:

Aptamers are short, single stranded nucleic acids which bind a wide range of different ligands with extraordinary high binding affinity and specificity. The steadily increasing number of aptamers is accompanied by an expanding range of applications in biotechnology. We will describe new developments in the field including the use of aptamers for conditional gene regulation and as biosensors. In addition, we will discuss the potential of aptamers as tags to visualize RNA and protein distribution in living cells and as therapeutics. Furthermore, we will consider biotechnological applications of riboswitches for gene regulation and as drug target.

Journal or Publication Title: Applied microbiology and biotechnology
Journal volume: 85
Number: 2
Divisions: 10 Department of Biology
10 Department of Biology > Synthetic Genetic Circuits
10 Department of Biology > RNA Biochemistry
Date Deposited: 22 Feb 2012 10:26
Export:
Suche nach Titel in: TUfind oder in Google
Send an inquiry Send an inquiry

Options (only for editors)
Show editorial Details Show editorial Details