Henkel, Michael ; Mitzner, David ; Henklein, Peter ; Meyer-Almes, Franz-Josef ; Moroni, Anna ; Difrancesco, Mattia L. ; Henkes, Leonhard M. ; Kreim, Michael ; Kast, Stefan M. ; Schubert, Ulrich ; Thiel, Gerhard (2010):
The proapoptotic influenza A virus protein PB1-F2 forms a nonselective ion channel.
In: PloS one, 5 (6), pp. e11112. ISSN 1932-6203,
[Article]
Abstract
The data support the idea that PB1-F2 is able to form protein channel pores with no appreciable selectivity in membranes and that the c-terminus is important for this function. This information could be important for drug development.
| Item Type: | Article |
|---|---|
| Erschienen: | 2010 |
| Creators: | Henkel, Michael ; Mitzner, David ; Henklein, Peter ; Meyer-Almes, Franz-Josef ; Moroni, Anna ; Difrancesco, Mattia L. ; Henkes, Leonhard M. ; Kreim, Michael ; Kast, Stefan M. ; Schubert, Ulrich ; Thiel, Gerhard |
| Title: | The proapoptotic influenza A virus protein PB1-F2 forms a nonselective ion channel. |
| Language: | English |
| Abstract: | The data support the idea that PB1-F2 is able to form protein channel pores with no appreciable selectivity in membranes and that the c-terminus is important for this function. This information could be important for drug development. |
| Journal or Publication Title: | PloS one |
| Journal Volume: | 5 |
| Issue Number: | 6 |
| Divisions: | 10 Department of Biology > Plant Membrane Biophysics ?? fb10_botanik ?? 10 Department of Biology |
| Date Deposited: | 21 Jun 2011 11:56 |
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