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Ultra-High-Resolution CT of the Head and Neck with Deep Learning Reconstruction—Assessment of Image Quality and Radiation Exposure and Intraindividual Comparison with Normal-Resolution CT

Altmann, Sebastian ; Abello Mercado, Mario A. ; Ucar, Felix A. ; Kronfeld, Andrea ; Al-Nawas, Bilal ; Mukhopadhyay, Anirban ; Booz, Christian ; Brockmann, Marc A. ; Othman, Ahmed E. (2023)
Ultra-High-Resolution CT of the Head and Neck with Deep Learning Reconstruction—Assessment of Image Quality and Radiation Exposure and Intraindividual Comparison with Normal-Resolution CT.
In: Diagnostics, 13 (9)
doi: 10.3390/diagnostics13091534
Article, Bibliographie

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Abstract

Objectives: To assess the benefits of ultra-high-resolution CT (UHR-CT) with deep learning– based image reconstruction engine (AiCE) regarding image quality and radiation dose and intraindividually compare it to normal-resolution CT (NR-CT). Methods: Forty consecutive patients with head and neck UHR-CT with AiCE for diagnosed head and neck malignancies and available prior NR-CT of a different scanner were retrospectively evaluated. Two readers evaluated subjective image quality using a 5-point Likert scale regarding image noise, image sharpness, artifacts, diagnostic acceptability, and assessability of various anatomic regions. For reproducibility, inter-reader agreement was analyzed. Furthermore, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and slope of the gray-value transition between different tissues were calculated. Radiation dose was evaluated by comparing CTDIvol, DLP, and mean effective dose values. Results: UHR-CT with AiCE reconstruction led to significant improvement in subjective (image noise and diagnostic acceptability: p < 0.000; ICC _ 0.91) and objective image quality (SNR: p < 0.000; CNR: p < 0.025) at significantly lower radiation doses (NR-CT 2.03 _ 0.14 mSv; UHR-CT 1.45 _ 0.11 mSv; p < 0.0001) compared to NR-CT. Conclusions: Compared to NR-CT, UHR-CT combined with AiCE provides superior image quality at a markedly lower radiation dose. With improved soft tissue assessment and potentially improved tumor detection, UHR-CT may add further value to the role of CT in the assessment of head and neck pathologies.

Item Type: Article
Erschienen: 2023
Creators: Altmann, Sebastian ; Abello Mercado, Mario A. ; Ucar, Felix A. ; Kronfeld, Andrea ; Al-Nawas, Bilal ; Mukhopadhyay, Anirban ; Booz, Christian ; Brockmann, Marc A. ; Othman, Ahmed E.
Type of entry: Bibliographie
Title: Ultra-High-Resolution CT of the Head and Neck with Deep Learning Reconstruction—Assessment of Image Quality and Radiation Exposure and Intraindividual Comparison with Normal-Resolution CT
Language: English
Date: 24 April 2023
Publisher: MDPI
Journal or Publication Title: Diagnostics
Volume of the journal: 13
Issue Number: 9
DOI: 10.3390/diagnostics13091534
Corresponding Links:
Abstract:

Objectives: To assess the benefits of ultra-high-resolution CT (UHR-CT) with deep learning– based image reconstruction engine (AiCE) regarding image quality and radiation dose and intraindividually compare it to normal-resolution CT (NR-CT). Methods: Forty consecutive patients with head and neck UHR-CT with AiCE for diagnosed head and neck malignancies and available prior NR-CT of a different scanner were retrospectively evaluated. Two readers evaluated subjective image quality using a 5-point Likert scale regarding image noise, image sharpness, artifacts, diagnostic acceptability, and assessability of various anatomic regions. For reproducibility, inter-reader agreement was analyzed. Furthermore, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and slope of the gray-value transition between different tissues were calculated. Radiation dose was evaluated by comparing CTDIvol, DLP, and mean effective dose values. Results: UHR-CT with AiCE reconstruction led to significant improvement in subjective (image noise and diagnostic acceptability: p < 0.000; ICC _ 0.91) and objective image quality (SNR: p < 0.000; CNR: p < 0.025) at significantly lower radiation doses (NR-CT 2.03 _ 0.14 mSv; UHR-CT 1.45 _ 0.11 mSv; p < 0.0001) compared to NR-CT. Conclusions: Compared to NR-CT, UHR-CT combined with AiCE provides superior image quality at a markedly lower radiation dose. With improved soft tissue assessment and potentially improved tumor detection, UHR-CT may add further value to the role of CT in the assessment of head and neck pathologies.

Uncontrolled Keywords: computed tomography, head and neck neoplasms, ultra-high resolution, image quality, radiation dose, deep learning
Identification Number: Artikel-ID: 1534
Additional Information:

This article belongs to the Special Issue Advances in CT Images

Divisions: 20 Department of Computer Science
20 Department of Computer Science > Interactive Graphics Systems
Date Deposited: 27 Nov 2023 14:39
Last Modified: 01 Aug 2024 09:01
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