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Freeform Membranes with Tunable Permeability in Microfluidics

Hirschwald, Lukas T. ; Brosch, Sebastian ; Linz, Georg ; Linkhorst, John ; Wessling, Matthias (2023)
Freeform Membranes with Tunable Permeability in Microfluidics.
In: Advanced Materials Technologies, 8 (9)
doi: 10.1002/admt.202201857
Article, Bibliographie

Abstract

Microfluidic systems offer a multitude of advantages over classical techniques in the fields of biomedical and chemical research. Unit operations such as sample pre-treatment, mixing, reactions, and especially separation and purification operations can be realized on microfluidic platforms enabling rapid prototyping and facile parallelization on the laboratory scale. However, the fabrication and integration of porous membranes in microfluidics poses several problems. Material development, membrane geometry, and membrane integration are three main questions to be addressed in this context. Here a durable and versatile method to anchor free-form membranes with tunable microgeometry to surfaces, enabling the fabrication of stable, multi-material microfluidic systems for different potential applications is shown. In addition, the influence of the macro- and microgeometry that is the shape and porosity of a membrane on key performance indicators such as diffusivity and permeation of tracer molecules is investigated. The presented characterization methods will enable a better understanding of microfluidic modules with incorporated membranes.

Item Type: Article
Erschienen: 2023
Creators: Hirschwald, Lukas T. ; Brosch, Sebastian ; Linz, Georg ; Linkhorst, John ; Wessling, Matthias
Type of entry: Bibliographie
Title: Freeform Membranes with Tunable Permeability in Microfluidics
Language: English
Date: 2023
Publisher: Wiley
Journal or Publication Title: Advanced Materials Technologies
Volume of the journal: 8
Issue Number: 9
DOI: 10.1002/admt.202201857
Abstract:

Microfluidic systems offer a multitude of advantages over classical techniques in the fields of biomedical and chemical research. Unit operations such as sample pre-treatment, mixing, reactions, and especially separation and purification operations can be realized on microfluidic platforms enabling rapid prototyping and facile parallelization on the laboratory scale. However, the fabrication and integration of porous membranes in microfluidics poses several problems. Material development, membrane geometry, and membrane integration are three main questions to be addressed in this context. Here a durable and versatile method to anchor free-form membranes with tunable microgeometry to surfaces, enabling the fabrication of stable, multi-material microfluidic systems for different potential applications is shown. In addition, the influence of the macro- and microgeometry that is the shape and porosity of a membrane on key performance indicators such as diffusivity and permeation of tracer molecules is investigated. The presented characterization methods will enable a better understanding of microfluidic modules with incorporated membranes.

Uncontrolled Keywords: freeform membranes, microfluidics, photopolymerization
Divisions: 16 Department of Mechanical Engineering
16 Department of Mechanical Engineering > Chair for Process Engineering of Electrochemical Systems
Date Deposited: 13 Sep 2023 11:13
Last Modified: 13 Sep 2023 11:13
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