Pitzer, Martin ; Kunitski, Maksim ; Johnson, Allan S. ; Jahnke, Till ; Sann, Hendrik ; Sturm, Felix ; Schmidt, Lothar Ph. H. ; Schmidt-Böcking, Horst ; Dörner, Reinhard ; Stohner, Jürgen ; Kiedrowski, Julia ; Reggelin, Michael ; Marquardt, Sebastian ; Schießer, Alexander ; Berger, Robert ; Schöffler, Markus S. (2023)
Direct Determination of Absolute Molecular Stereochemistry in Gas Phase by Coulomb Explosion Imaging.
In: Science, 2013, 341 (6150)
doi: 10.26083/tuprints-00024248
Article, Secondary publication, Postprint
 | There is a more recent version of this item available. |
Abstract
Bijvoet’s method, which makes use of anomalous x-ray diffraction or dispersion, is the standard means of directly determining the absolute (stereochemical) configuration of molecules, but it requires crystalline samples and often proves challenging in structures exclusively comprising light atoms. Herein, we demonstrate a mass spectrometry approach that directly images the absolute configuration of individual molecules in the gas phase by cold target recoil ion momentum spectroscopy after laser ionization–induced Coulomb explosion. This technique is applied to the prototypical chiral molecule bromochlorofluoromethane and the isotopically chiral methane derivative bromodichloromethane.
| Item Type: | Article |
|---|---|
| Erschienen: | 2023 |
| Creators: | Pitzer, Martin ; Kunitski, Maksim ; Johnson, Allan S. ; Jahnke, Till ; Sann, Hendrik ; Sturm, Felix ; Schmidt, Lothar Ph. H. ; Schmidt-Böcking, Horst ; Dörner, Reinhard ; Stohner, Jürgen ; Kiedrowski, Julia ; Reggelin, Michael ; Marquardt, Sebastian ; Schießer, Alexander ; Berger, Robert ; Schöffler, Markus S. |
| Type of entry: | Secondary publication |
| Title: | Direct Determination of Absolute Molecular Stereochemistry in Gas Phase by Coulomb Explosion Imaging |
| Language: | English |
| Date: | 2023 |
| Place of Publication: | Darmstadt |
| Year of primary publication: | 2013 |
| Publisher: | American Association for the Advancement of Science |
| Journal or Publication Title: | Science |
| Volume of the journal: | 341 |
| Issue Number: | 6150 |
| DOI: | 10.26083/tuprints-00024248 |
| URL / URN: | https://tuprints.ulb.tu-darmstadt.de/24248 |
| Corresponding Links: | |
| Origin: | Secondary publication service |
| Abstract: | Bijvoet’s method, which makes use of anomalous x-ray diffraction or dispersion, is the standard means of directly determining the absolute (stereochemical) configuration of molecules, but it requires crystalline samples and often proves challenging in structures exclusively comprising light atoms. Herein, we demonstrate a mass spectrometry approach that directly images the absolute configuration of individual molecules in the gas phase by cold target recoil ion momentum spectroscopy after laser ionization–induced Coulomb explosion. This technique is applied to the prototypical chiral molecule bromochlorofluoromethane and the isotopically chiral methane derivative bromodichloromethane. |
| Status: | Postprint |
| URN: | urn:nbn:de:tuda-tuprints-242489 |
| Classification DDC: | 500 Science and mathematics > 540 Chemistry |
| Divisions: | 07 Department of Chemistry 07 Department of Chemistry > Clemens-Schöpf-Institut > Fachgebiet Biochemie 07 Department of Chemistry > Clemens-Schöpf-Institut 07 Department of Chemistry > Clemens-Schöpf-Institut > Organ Chemistry |
| Date Deposited: | 10 Jul 2023 10:01 |
| Last Modified: | 02 Aug 2024 12:53 |
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| Suche nach Titel in: | TUfind oder in Google |
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