Wesarg, Stefan ; Kafchitsas, Konstantinos ; Erdt, Marius ; Khan, M. Fawad (2010)
CAD of Osteoporosis in Vertebrae Using Dual-energy CT.
Twenty-Third IEEE Symposium on Computer-Based Medical Systems.
Conference or Workshop Item, Bibliographie
Abstract
The assessment of bone mineral density (BMD) in vertebrae is critical for the diagnosis of osteoporosis. Recent developments in dual-source CT allow for the simultaneous acquisition of two image data sets with different X-ray tube energies - dual-energy CT (DECT). We present a comprehensive approach for assessing the density of the trabecular bone in vertebrae of the spine based on DECT image data. For this, we apply and combine methods from different areas: the deformation of a template mesh for delineating the structures of interest, a biophysical model of the trabecular bone for the computation of BMD values, and different visualization approaches for the display of the results. In addition, we investigate the correlation between the computed BMD values with concurrently measured pull-out forces for pedicle screws. We show that there is a linear correlation between both measures and thus, DECT provides correct BMD values for the trabecular bone. We conclude that our approach enables the radiologist to diagnose osteoporosis based on DECT image data which has the potential to replace the current gold standard dual-energy X-ray absorptiometry.
| Item Type: | Conference or Workshop Item |
|---|---|
| Erschienen: | 2010 |
| Creators: | Wesarg, Stefan ; Kafchitsas, Konstantinos ; Erdt, Marius ; Khan, M. Fawad |
| Type of entry: | Bibliographie |
| Title: | CAD of Osteoporosis in Vertebrae Using Dual-energy CT |
| Language: | English |
| Date: | 2010 |
| Publisher: | IEEE Computer Society, Los Alamitos, Calif. |
| Event Title: | Twenty-Third IEEE Symposium on Computer-Based Medical Systems |
| Abstract: | The assessment of bone mineral density (BMD) in vertebrae is critical for the diagnosis of osteoporosis. Recent developments in dual-source CT allow for the simultaneous acquisition of two image data sets with different X-ray tube energies - dual-energy CT (DECT). We present a comprehensive approach for assessing the density of the trabecular bone in vertebrae of the spine based on DECT image data. For this, we apply and combine methods from different areas: the deformation of a template mesh for delineating the structures of interest, a biophysical model of the trabecular bone for the computation of BMD values, and different visualization approaches for the display of the results. In addition, we investigate the correlation between the computed BMD values with concurrently measured pull-out forces for pedicle screws. We show that there is a linear correlation between both measures and thus, DECT provides correct BMD values for the trabecular bone. We conclude that our approach enables the radiologist to diagnose osteoporosis based on DECT image data which has the potential to replace the current gold standard dual-energy X-ray absorptiometry. |
| Uncontrolled Keywords: | Forschungsgruppe Medical Computing (MECO), Computer aided diagnosis, Computed tomography (CT), Medical image processing, Bone mineral density (BMD) |
| Divisions: | 20 Department of Computer Science 20 Department of Computer Science > Interactive Graphics Systems |
| Date Deposited: | 12 Nov 2018 11:16 |
| Last Modified: | 12 Nov 2018 11:16 |
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