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Einträge mit Organisationseinheit "10 Fachbereich Biologie > Zelluläre Neurophysiologie"

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B

Barnes, William :
Reversible Visual Hemineglect: the Role of Neural Oscillations in Primary Visual Cortex.
[Online-Edition: http://tuprints.ulb.tu-darmstadt.de/5193]
Technische Universität , Darmstadt
[Dissertation], (2014)

Bressel, Olaf Christian :
Axonal wiring in the mouse olfactory system.
[Online-Edition: http://tuprints.ulb.tu-darmstadt.de/5191]
Technische Universität , Darmstadt
[Dissertation], (2015)

Betz, Heinrich ; Laube, Bodo :
Glycine receptors: recent insights into their structural organization and functional diversity.
In: Journal of neurochemistry, 97 (6) pp. 1600-10. ISSN 0022-3042
[Artikel], (2006)

Büttner, C. ; Sadtler, S. ; Leyendecker, A. ; Laube, Bodo ; Griffon, N. ; Betz, H. ; Schmalzing, G. :
Ubiquitination precedes internalization and proteolytic cleavage of plasma membrane-bound glycine receptors.
In: The Journal of biological chemistry, 276 (46) pp. 42978-85. ISSN 0021-9258
[Artikel], (2001)

Betz, H. ; Kuhse, J. ; Schmieden, V. ; Laube, Bodo ; Kirsch, J. ; Harvey, R. J. :
Structure and functions of inhibitory and excitatory glycine receptors.
In: Annals of the New York Academy of Sciences, 868 pp. 667-76. ISSN 0077-8923
[Artikel], (1999)

Betz, H. ; Kuhse, J. ; Fischer, M. ; Schmieden, V. ; Laube, Bodo ; Kuryatov, A. ; Langosch, D. ; Meyer, G. ; Bormann, J. ; Rundström, N. :
Structure, diversity and synaptic localization of inhibitory glycine receptors.
In: Journal of physiology, Paris, 88 (4) pp. 243-8. ISSN 0928-4257
[Artikel], (1994)

C

Costa, Blaise Mathias ; Irvine, Mark W. ; Fang, Guangyu ; Eaves, Richard J. ; Mayo-Martin, Maria Belen ; Laube, Bodo ; Jane, David E. ; Monaghan, Daniel T. :
Structure-activity relationships for allosteric NMDA receptor inhibitors based on 2-naphthoic acid.
In: Neuropharmacology, 62 (4) pp. 1730-6. ISSN 1873-7064
[Artikel], (2012)

D

Dutertre, Sébastien ; Drwal, Malgorzata ; Laube, Bodo ; Betz, Heinrich :
Probing the pharmacological properties of distinct subunit interfaces within heteromeric glycine receptors reveals a functional ββ agonist binding site.
In: Journal of neurochemistry, 122 (1) pp. 38-47. ISSN 1471-4159
[Artikel], (2012)

Dutertre, S. ; Kuzmin, D. ; Laube, Bodo ; Betz, H.
Lajtha, A. (ed.) :

Inhibitory glycine receptors. Neural signal mechanism "Channels: structure, cellular function and disorder".
In: Handbook of Neurochemistry and Molecular Neurobiology. , pp. 375-390.
[Buchkapitel], (2009)

E

Endele, Sabine ; Rosenberger, Georg ; Geider, Kirsten ; Popp, Bernt ; Tamer, Ceyhun ; Stefanova, Irina ; Milh, Mathieu ; Kortüm, Fanny ; Fritsch, Angela ; Pientka, Friederike K. ; Hellenbroich, Yorck ; Kalscheuer, Vera M. ; Kohlhase, Jürgen ; Moog, Ute ; Rappold, Gudrun ; Rauch, Anita ; Ropers, Hans-Hilger ; von Spiczak, Sarah ; Tönnies, Holger ; Villeneuve, Nathalie ; Villard, Laurent ; Zabel, Bernhard ; Zenker, Martin ; Laube, Bodo ; Reis, André ; Wieczorek, Dagmar ; Van Maldergem, Lionel ; Kutsche, Kerstin :
Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes.
In: Nature genetics, 42 (11) pp. 1021-6. ISSN 1546-1718
[Artikel], (2010)

F

Foucaud, Bernard ; Laube, Bodo ; Schemm, Rudolf ; Kreimeyer, Annett ; Goeldner, Maurice ; Betz, Heinrich :
Structural model of the N-methyl-D-aspartate receptor glycine site probed by site-directed chemical coupling.
In: The Journal of biological chemistry, 278 (26) pp. 24011-7. ISSN 0021-9258
[Artikel], (2003)

G

Geider, Kirsten :
Ionotropic glutamate receptor dysfunction in pediatric neurodevelopment.
[Online-Edition: http://tuprints.ulb.tu-darmstadt.de/4411]
TU Darmstadt
[Dissertation], (2015)

Grudzinska, Joanna ; Schumann, Tanja ; Schemm, Rudolf ; Betz, Heinrich ; Laube, Bodo :
Mutations within the agonist-binding site convert the homomeric alpha1 glycine receptor into a Zn2+-activated chloride channel.
In: Channels (Austin, Tex.), 2 (1) pp. 13-8. ISSN 1933-6969
[Artikel], (2008)

Grudzinska, Joanna ; Schemm, Rudolf ; Haeger, Svenja ; Nicke, Annette ; Schmalzing, Guenther ; Betz, Heinrich ; Laube, Bodo :
The beta subunit determines the ligand binding properties of synaptic glycine receptors.
In: Neuron, 45 (5) pp. 727-39. ISSN 0896-6273
[Artikel], (2005)

Gomeza, Jesús ; Ohno, Koji ; Hülsmann, Swen ; Armsen, Wencke ; Eulenburg, Volker ; Richter, Diethelm W. ; Laube, Bodo ; Betz, Heinrich :
Deletion of the mouse glycine transporter 2 results in a hyperekplexia phenotype and postnatal lethality.
In: Neuron, 40 (4) pp. 797-806. ISSN 0896-6273
[Artikel], (2003)

Garcia-Guzman, M. ; Soto, F. ; Laube, Bodo ; Stühmer, W. :
Molecular cloning and functional expression of a novel rat heart P2X purinoceptor.
In: FEBS letters, 388 (2-3) pp. 123-7. ISSN 0014-5793
[Artikel], (1996)

H

Haeger, Svenja ; Kuzmin, Dmitry ; Detro-Dassen, Silvia ; Lang, Niklas ; Kilb, Michael ; Tsetlin, Victor ; Betz, Heinrich ; Laube, Bodo ; Schmalzing, Günther :
An intramembrane aromatic network determines pentameric assembly of Cys-loop receptors.
In: Nature structural & molecular biology, 17 (1) pp. 90-8. ISSN 1545-9985
[Artikel], (2010)

Hirzel, Klaus ; Müller, Ulrike ; Latal, A.Tobias ; Hülsmann, Swen ; Grudzinska, Joanna ; Seeliger, Mathias W. ; Betz, Heinrich ; Laube, Bodo :
Hyperekplexia phenotype of glycine receptor alpha1 subunit mutant mice identifies Zn(2+) as an essential endogenous modulator of glycinergic neurotransmission.
In: Neuron, 52 (4) pp. 679-90. ISSN 0896-6273
[Artikel], (2006)

Harvey, R. J. ; Schmieden, V. ; Von Holst, A. ; Laube, Bodo ; Rohrer, H. ; Betz, H. :
Glycine receptors containing the alpha4 subunit in the embryonic sympathetic nervous system, spinal cord and male genital ridge.
In: The European journal of neuroscience, 12 (3) pp. 994-1001. ISSN 0953-816X
[Artikel], (2000)

Honer, M. ; Benke, D. ; Laube, Bodo ; Kuhse, J. ; Heckendorn, R. ; Allgeier, H. ; Angst, C. ; Monyer, H. ; Seeburg, P. H. ; Betz, H. ; Möhler, H. :
Differentiation of glycine antagonist sites of N-methyl-D-aspartate receptor subtypes. Preferential interaction of CGP 61594 with NR1/2B receptors.
In: The Journal of biological chemistry, 273 (18) pp. 11158-63. ISSN 0021-9258
[Artikel], (1998)

Hirai, H. ; Kirsch, J. ; Laube, Bodo ; Betz, H. ; Kuhse, J. :
The glycine binding site of the N-methyl-D-aspartate receptor subunit NR1: identification of novel determinants of co-agonist potentiation in the extracellular M3-M4 loop region.
In: Proceedings of the National Academy of Sciences of the United States of America, 93 (12) pp. 6031-6. ISSN 0027-8424
[Artikel], (1996)

I

Ivanovic, A. ; Reiländer, H. ; Laube, Bodo ; Kuhse, J. :
Expression and initial characterization of a soluble glycine binding domain of the N-methyl-D-aspartate receptor NR1 subunit.
In: The Journal of biological chemistry, 273 (32) pp. 19933-7. ISSN 0021-9258
[Artikel], (1998)

K

Kallenborn-Gerhardt, Wiebke ; Lu, Ruirui ; Lorenz, Jana ; Gao, Wei ; Weiland, Jessica ; Del Turco, Domenico ; Deller, Thomas ; Laube, Bodo ; Betz, Heinrich ; Geisslinger, Gerd ; Schmidtko, Achim :
Prolonged zymosan-induced inflammatory pain hypersensitivity in mice lacking glycine receptor alpha2.
In: Behavioural brain research, 226 (1) pp. 106-11. ISSN 1872-7549
[Artikel], (2012)

Kondratskaya, Elena L. ; Betz, Heinrich ; Krishtal, Oleg A. ; Laube, Bodo :
The beta subunit increases the ginkgolide B sensitivity of inhibitory glycine receptors.
In: Neuropharmacology, 49 (6) pp. 945-51. ISSN 0028-3908
[Artikel], (2005)

Kreimeyer, A. ; Laube, Bodo ; Sturgess, M. ; Goeldner, M. ; Foucaud, B. :
Reactive affinity probes for the mapping of the glycine-binding site of the NMDA receptor NR1 subunit.
In: Journal of receptor and signal transduction research, 19 (1-4) pp. 547-57. ISSN 1079-9893
[Artikel], (1999)

Kreimeyer, A. ; Laube, Bodo ; Sturgess, M. ; Goeldner, M. ; Foucaud, B. :
Evaluation and biological properties of reactive ligands for the mapping of the glycine site on the N-methyl-D-aspartate (NMDA) receptor.
In: Journal of medicinal chemistry, 42 (21) pp. 4394-404. ISSN 0022-2623
[Artikel], (1999)

Kins, S. ; Kuhse, J. ; Laube, Bodo ; Betz, H. ; Kirsch, J. :
Incorporation of a gephyrin-binding motif targets NMDA receptors to gephyrin-rich domains in HEK 293 cells.
In: The European journal of neuroscience, 11 (2) pp. 740-4. ISSN 0953-816X
[Artikel], (1999)

Kneussel, M. ; Brandstätter, J. H. ; Laube, Bodo ; Stahl, S. ; Müller, U. ; Betz, H. :
Loss of postsynaptic GABA(A) receptor clustering in gephyrin-deficient mice.
In: The Journal of neuroscience : the official journal of the Society for Neuroscience, 19 (21) pp. 9289-97. ISSN 1529-2401
[Artikel], (1999)

Kuryatov, A. ; Laube, Bodo ; Betz, H. ; Kuhse, J. :
Mutational analysis of the glycine-binding site of the NMDA receptor: structural similarity with bacterial amino acid-binding proteins.
In: Neuron, 12 (6) pp. 1291-300. ISSN 0896-6273
[Artikel], (1994)

Kuhse, J. ; Laube, Bodo ; Magalei, D. ; Betz, H. :
Assembly of the inhibitory glycine receptor: identification of amino acid sequence motifs governing subunit stoichiometry.
In: Neuron, 11 (6) pp. 1049-56. ISSN 0896-6273
[Artikel], (1993)

L

Lemke, Johannes R. ; Geider, Kirsten ; Helbig, Katherine L. ; Heyne, Henrike O. ; Schütz, Hannah ; Hentschel, Julia ; Courage, Carolina ; Depienne, Christel ; Nava, Caroline ; Heron, Delphine ; Møller, Rikke S. ; Hjalgrim, Helle ; Lal, Dennis ; Neubauer, Bernd A. ; Nürnberg, Peter ; Thiele, Holger ; Kurlemann, Gerhard ; Arnold, Georgianne L. ; Bhambhani, Vikas ; Bartholdi, Deborah ; Pedurupillay, Christeen Ramane J. ; Misceo, Doriana ; Frengen, Eirik ; Strømme, Petter ; Dlugos, Dennis J. ; Doherty, Emily S. ; Bijlsma, Emilia K. ; Ruivenkamp, Claudia A. ; Hoffer, Mariette J. V. ; Goldstein, Amy ; Rajan, Deepa S. ; Narayanan, Vinodh ; Ramsey, Keri ; Belnap, Newell ; Schrauwen, Isabelle ; Richholt, Ryan ; Koeleman, Bobby P. C. ; Sá, Joaquim ; Mendonça, Carla ; de Kovel, Carolien G. F. ; Weckhuysen, Sarah ; Hardies, Katia ; De Jonghe, Peter ; De Meirleir, Linda ; Milh, Mathieu ; Badens, Catherine ; Lebrun, Marine ; Busa, Tiffany ; Francannet, Christine ; Piton, Amélie ; Riesch, Erik ; Biskup, Saskia ; Vogt, Heinrich ; Dorn, Thomas ; Helbig, Ingo ; Michaud, Jacques L. ; Laube, Bodo ; Syrbe, Steffen :
Delineating the GRIN1 phenotypic spectrum: A distinct genetic NMDA receptor encephalopathy.
In: Neurology, 86 (23) pp. 2171-8. ISSN 1526-632X
[Artikel], (2016)

Lynagh, Timothy ; Beech, Robin N. ; Lalande, Maryline J. ; Keller, Kevin ; Cromer, Brett A. ; Wolstenholme, Adrian J. ; Laube, Bodo :
Molecular basis for convergent evolution of glutamate recognition by pentameric ligand-gated ion channels.
In: Scientific reports, 24 (5) p. 8558. ISSN 2045-2322
[Artikel], (2015)

Lynagh, Timothy ; Laube, Bodo :
Opposing effects of the anesthetic propofol at pentameric ligand-gated ion channels mediated by a common site.
In: The Journal of neuroscience : the official journal of the Society for Neuroscience, 34 (6) pp. 2155-9. ISSN 1529-2401
[Artikel], (2014)

Lemke, Johannes R. ; Hendrickx, Rik ; Geider, Kirsten ; Laube, Bodo ; Schwake, Michael ; Harvey, Robert J. ; James, Victoria M. ; Pepler, Alex ; Steiner, Isabelle ; Hörtnagel, Konstanze ; Neidhardt, John ; Ruf, Susanne ; Wolff, Markus ; Bartholdi, Deborah ; Caraballo, Roberto ; Platzer, Konrad ; Suls, Arvid ; De Jonghe, Peter ; Biskup, Saskia ; Weckhuysen, Sarah :
GRIN2B mutations in West syndrome and intellectual disability with focal epilepsy.
In: Annals of neurology, 75 (1) pp. 147-54. ISSN 1531-8249
[Artikel], (2014)

Längle, Adriana :
Ionotrope Glutamatrezeptoren als Targetstrukturen zur Modulation der Strahlenwirkung bei Glioblastomzellen.
[Online-Edition: http://tuprints.ulb.tu-darmstadt.de/4004]
TU Darmstadt
[Dissertation], (2014)

Lynagh, Timothy ; Cromer, Brett A. ; Dufour, Vanessa ; Laube, Bodo :
Comparative pharmacology of flatworm and roundworm glutamate-gated chloride channels: Implications for potential anthelmintics.
In: International journal for parasitology. Drugs and drug resistance, 4 (3) pp. 244-55. ISSN 2211-3207
[Artikel], (2014)

Lynagh, Timothy ; Kunz, Alexander ; Laube, Bodo :
Propofol modulation of α1 glycine receptors does not require a structural transition at adjacent subunits that is crucial to agonist-induced activation.
In: ACS chemical neuroscience, 4 (11) pp. 1469-78. ISSN 1948-7193
[Artikel], (2013)

Lemke, Johannes R. ; Lal, Dennis ; Reinthaler, Eva M. ; Steiner, Isabelle ; Nothnagel, Michael ; Alber, Michael ; Geider, Kirsten ; Laube, Bodo ; Schwake, Michael ; Finsterwalder, Katrin ; Franke, Andre ; Schilhabel, Markus ; Jähn, Johanna A. ; Muhle, Hiltrud ; Boor, Rainer ; Van Paesschen, Wim ; Caraballo, Roberto ; Fejerman, Natalio ; Weckhuysen, Sarah ; De Jonghe, Peter ; Larsen, Jan ; Møller, Rikke S. ; Hjalgrim, Helle ; Addis, Laura ; Tang, Shan ; Hughes, Elaine ; Pal, Deb K. ; Veri, Kadi ; Vaher, Ulvi ; Talvik, Tiina ; Dimova, Petia ; Guerrero López, Rosa ; Serratosa, José M. ; Linnankivi, Tarja ; Lehesjoki, Anna-Elina ; Ruf, Susanne ; Wolff, Markus ; Buerki, Sarah ; Wohlrab, Gabriele ; Kroell, Judith ; Datta, Alexandre N. ; Fiedler, Barbara ; Kurlemann, Gerhard ; Kluger, Gerhard ; Hahn, Andreas ; Haberlandt, D. Edda ; Kutzer, Christina ; Sperner, Jürgen ; Becker, Felicitas ; Weber, Yvonne G. ; Feucht, Martha ; Steinböck, Hannelore ; Neophythou, Birgit ; Ronen, Gabriel M. ; Gruber-Sedlmayr, Ursula ; Geldner, Julia ; Harvey, Robert J. ; Hoffmann, Per ; Herms, Stefan ; Altmüller, Janine ; Toliat, Mohammad R. ; Thiele, Holger ; Nürnberg, Peter ; Wilhelm, Christian ; Stephani, Ulrich ; Helbig, Ingo ; Lerche, Holger ; Zimprich, Fritz ; Neubauer, Bernd A. ; Biskup, Saskia ; von Spiczak, Sarah :
Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes.
In: Nature genetics, 45 (9) pp. 1067-72. ISSN 1546-1718
[Artikel], (2013)

Laube, Bodo ; Betz, Heinrich :
Die duale Rolle des Neurotransmitters Glyzin im zentralen Nervensystem.
[Online-Edition: http://www.mpg.de/312638/forschungsSchwerpunkt1]
In: Jahrbuch 2009 der Max-Planck-Gesellschaft
[Artikel], (2009)

Laube, Bodo :
Dr. Jekyll & Mr. Hyde - das janusköpfige Zink.
In: BIOforum, 30 (3) pp. 25-27.
[Artikel], (2007)

Laube, Bodo ; Schemm, Rudolf ; Betz, Heinrich :
Molecular determinants of ligand discrimination in the glutamate-binding pocket of the NMDA receptor.
In: Neuropharmacology, 47 (7) pp. 994-1007. ISSN 0028-3908
[Artikel], (2004)

Laube, Bodo ; Betz, H.
Lennarz, William (ed.) :

Glycine receptors.
In: Encyclopedia of Biological Chemistry. Elsevier , pp. 237-243. ISBN 978-0-12-443710-4
[Buchkapitel], (2004)

Laube, Bodo ; Maksay, Gábor ; Schemm, Rudolf ; Betz, Heinrich :
Modulation of glycine receptor function: a novel approach for therapeutic intervention at inhibitory synapses?
In: Trends in pharmacological sciences, 23 (11) pp. 519-27. ISSN 0165-6147
[Artikel], (2002)

Laube, Bodo :
Potentiation of inhibitory glycinergic neurotransmission by Zn2+: a synergistic interplay between presynaptic P2X2 and postsynaptic glycine receptors.
In: The European journal of neuroscience, 16 (6) pp. 1025-36. ISSN 0953-816X
[Artikel], (2002)

Laube, Bodo ; Kuhse, J. ; Betz, H. :
Kinetic and mutational analysis of Zn2+ modulation of recombinant human inhibitory glycine receptors.
In: The Journal of physiology, 522 Pt pp. 215-30. ISSN 0022-3751
[Artikel], (2000)

Laube, Bodo ; Betz, H. :
Purification and heterologous expression of inhibitory glycine receptors.
In: Methods in enzymology, 294 pp. 260-73. ISSN 0076-6879
[Artikel], (1999)

Laube, Bodo ; Kuhse, J. ; Betz, H. :
Evidence for a tetrameric structure of recombinant NMDA receptors.
In: The Journal of neuroscience : the official journal of the Society for Neuroscience, 18 (8) pp. 2954-61. ISSN 0270-6474
[Artikel], (1998)

Laube, Bodo ; Hirai, H. ; Sturgess, M. ; Betz, H. ; Kuhse, J. :
Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit.
In: Neuron, 18 (3) pp. 493-503. ISSN 0896-6273
[Artikel], (1997)

Laube, Bodo ; Langosch, D. ; Betz, H. ; Schmieden, V. :
Hyperekplexia mutations of the glycine receptor unmask the inhibitory subsite for beta-amino-acids.
In: Neuroreport, 6 (6) pp. 897-900. ISSN 0959-4965
[Artikel], (1995)

Laube, Bodo ; Kuhse, J. ; Rundström, N. ; Kirsch, J. ; Schmieden, V. ; Betz, H. :
Modulation by zinc ions of native rat and recombinant human inhibitory glycine receptors.
In: The Journal of physiology, 483 pp. 613-9. ISSN 0022-3751
[Artikel], (1995)

Langosch, D. ; Laube, Bodo ; Rundström, N. ; Schmieden, V. ; Bormann, J. ; Betz, H. :
Decreased agonist affinity and chloride conductance of mutant glycine receptors associated with human hereditary hyperekplexia.
In: The EMBO journal, 13 (18) pp. 4223-8. ISSN 0261-4189
[Artikel], (1994)

Laube, Bodo ; Kuryatov, A. ; Kuhse, J. ; Betz, H. :
Glycine-glutamate interactions at the NMDA receptor: role of cysteine residues.
In: FEBS letters, 335 (3) pp. 331-4. ISSN 0014-5793
[Artikel], (1993)

M

Mesic, Ivana ; Madry, Christian ; Geider, Kirsten ; Bernhard, Max ; Betz, Heinrich ; Laube, Bodo :
The N-terminal domain of the GluN3A subunit determines the efficacy of glycine-activated NMDA receptors.
In: Neuropharmacology, 105 pp. 133-141. ISSN 1873-7064
[Artikel], (2016)

Madry, Christian ; Betz, Heinrich ; Geiger, Jörg R. P. ; Laube, Bodo :
Potentiation of Glycine-Gated NR1/NR3A NMDA Receptors Relieves Ca-Dependent Outward Rectification.
In: Frontiers in molecular neuroscience, 3 p. 6. ISSN 1662-5099
[Artikel], (2010)

Maksay, Gábor ; Laube, Bodo ; Schemm, Rudolf ; Grudzinska, Joanna ; Drwal, Malgorzata ; Betz, Heinrich :
Different binding modes of tropeines mediating inhibition and potentiation of alpha1 glycine receptors.
In: Journal of neurochemistry, 109 (6) pp. 1725-32. ISSN 1471-4159
[Artikel], (2009)

Madry, Christian ; Betz, Heinrich ; Geiger, Jörg R. P. ; Laube, Bodo :
Supralinear potentiation of NR1/NR3A excitatory glycine receptors by Zn2+ and NR1 antagonist.
In: Proceedings of the National Academy of Sciences of the United States of America, 105 (34) pp. 12563-8. ISSN 1091-6490
[Artikel], (2008)

Maksay, Gábor ; Bíró, Tímea ; Laube, Bodo ; Nemes, Péter :
Hyperekplexia mutation R271L of alpha1 glycine receptors potentiates allosteric interactions of nortropeines, propofol and glycine with [3H]strychnine binding.
In: Neurochemistry international, 52 (1-2) pp. 235-40. ISSN 0197-0186
[Artikel], (2008)

Madry, Christian ; Mesic, Ivana ; Betz, Heinrich ; Laube, Bodo :
The N-terminal domains of both NR1 and NR2 subunits determine allosteric Zn2+ inhibition and glycine affinity of N-methyl-D-aspartate receptors.
In: Molecular pharmacology, 72 (6) pp. 1535-44. ISSN 1521-0111
[Artikel], (2007)

Madry, Christian ; Mesic, Ivana ; Bartholomäus, Ingo ; Nicke, Annette ; Betz, Heinrich ; Laube, Bodo :
Principal role of NR3 subunits in NR1/NR3 excitatory glycine receptor function.
In: Biochemical and biophysical research communications, 354 (1) pp. 102-8. ISSN 0006-291X
[Artikel], (2007)

Maier, Wolfgang ; Schemm, Rudolf ; Grewer, Christof ; Laube, Bodo :
Disruption of interdomain interactions in the glutamate binding pocket affects differentially agonist affinity and efficacy of N-methyl-D-aspartate receptor activation.
In: The Journal of biological chemistry, 282 (3) pp. 1863-72. ISSN 0021-9258
[Artikel], (2007)

Maier, Wolfgang ; Corrie, John E. T. ; Papageorgiou, George ; Laube, Bodo ; Grewer, Christof :
Comparative analysis of inhibitory effects of caged ligands for the NMDA receptor.
In: Journal of neuroscience methods, 142 (1) pp. 1-9. ISSN 0165-0270
[Artikel], (2005)

Maksay, Gábor ; Bíró, Tímea ; Laube, Bodo :
Hyperekplexia mutation of glycine receptors: decreased gating efficacy with altered binding thermodynamics.
In: Biochemical pharmacology, 64 (2) pp. 285-8. ISSN 0006-2952
[Artikel], (2002)

Maksay, G. ; Laube, Bodo ; Betz, H. :
Subunit-specific modulation of glycine receptors by neurosteroids.
In: Neuropharmacology, 41 (3) pp. 369-76. ISSN 0028-3908
[Artikel], (2001)

Maksay, G. ; Laube, Bodo ; Betz, H. :
Selective blocking effects of tropisetron and atropine on recombinant glycine receptors.
In: Journal of neurochemistry, 73 (2) pp. 802-6. ISSN 0022-3042
[Artikel], (1999)

Müller, M. ; Laube, Bodo ; Burda, H. ; Bruns, V. :
Structure and function of the cochlea in the African mole rat (Cryptomys hottentotus): evidence for a low frequency acoustic fovea.
In: Journal of comparative physiology. A, Sensory, neural, and behavioral physiology, 171 (4) pp. 469-76. ISSN 0340-7594
[Artikel], (1992)

N

Nikolic, Z. ; Laube, Bodo ; Weber, R. G. ; Lichter, P. ; Kioschis, P. ; Poustka, A. ; Mülhardt, C. ; Becker, C. M. :
The human glycine receptor subunit alpha3. Glra3 gene structure, chromosomal localization, and functional characterization of alternative transcripts.
In: The Journal of biological chemistry, 273 (31) pp. 19708-14. ISSN 0021-9258
[Artikel], (1998)

O

O'Shea, Sean Michael ; Becker, Lore ; Weiher, Hans ; Betz, Heinrich ; Laube, Bodo :
Propofol restores the function of "hyperekplexic" mutant glycine receptors in Xenopus oocytes and mice.
In: The Journal of neuroscience : the official journal of the Society for Neuroscience, 24 (9) pp. 2322-7. ISSN 1529-2401
[Artikel], (2004)

Ortinau, Stefanie ; Laube, Bodo ; Zimmermann, Herbert :
ATP inhibits NMDA receptors after heterologous expression and in cultured hippocampal neurons and attenuates NMDA-mediated neurotoxicity.
In: The Journal of neuroscience : the official journal of the Society for Neuroscience, 23 (12) pp. 4996-5003. ISSN 1529-2401
[Artikel], (2003)

P

Platzer, Konrad ; Yuan, Hongjie ; Schütz, Hannah ; Winschel, Alexander ; Chen, Wenjuan ; Hu, Chun ; Kusumoto, Hirofumi ; Heyne, Henrike O. ; Helbig, Katherine L. ; Tang, Sha ; Willing, Marcia C. ; Tinkle, Brad T. ; Adams, Darius J. ; Depienne, Christel ; Keren, Boris ; Mignot, Cyril ; Frengen, Eirik ; Strømme, Petter ; Biskup, Saskia ; Döcker, Dennis ; Strom, Tim M. ; Mefford, Heather C. ; Myers, Candace T. ; Muir, Alison M. ; LaCroix, Amy ; Sadleir, Lynette ; Scheffer, Ingrid E. ; Brilstra, Eva ; van Haelst, Mieke M. ; van der Smagt, Jasper J. ; Bok, Levinus A. ; Møller, Rikke S. ; Jensen, Uffe B. ; Millichap, John J. ; Berg, Anne T. ; Goldberg, Ethan M. ; De Bie, Isabelle ; Fox, Stephanie ; Major, Philippe ; Jones, Julie R. ; Zackai, Elaine H. ; Abou Jamra, Rami ; Rolfs, Arndt ; Leventer, Richard J. ; Lawson, John A. ; Roscioli, Tony ; Jansen, Floor E. ; Ranza, Emmanuelle ; Korff, Christian M. ; Lehesjoki, Anna-Elina ; Courage, Carolina ; Linnankivi, Tarja ; Smith, Douglas R. ; Stanley, Christine ; Mintz, Mark ; McKnight, Dianalee ; Decker, Amy ; Tan, Wen-Hann ; Tarnopolsky, Mark A. ; Brady, Lauren I. ; Wolff, Markus ; Dondit, Lutz ; Pedro, Helio F. ; Parisotto, Sarah E. ; Jones, Kelly L. ; Patel, Anup D. ; Franz, David N. ; Vanzo, Rena ; Marco, Elysa ; Ranells, Judith D. ; Di Donato, Nataliya ; Dobyns, William B. ; Laube, Bodo ; Traynelis, Stephen F. ; Lemke, Johannes R. :
GRIN2B encephalopathy: novel findings on phenotype, variant clustering, functional consequences and treatment aspects.
In: Journal of medical genetics, 54 (7) pp. 460-470. ISSN 1468-6244
[Artikel], (2017)

Pult, Frauke ; Fallah, Ghada ; Braam, Ursula ; Detro-Dassen, Silvia ; Niculescu, Cristina ; Laube, Bodo ; Schmalzing, Günther :
Robust post-translocational N-glycosylation at the extreme C-terminus of membrane and secreted proteins in Xenopus laevis oocytes and HEK293 cells.
In: Glycobiology, 21 (9) pp. 1147-1160. ISSN 1460-2423
[Artikel], (2011)

Papadopoulos, Theofilos ; Korte, Martin ; Eulenburg, Volker ; Kubota, Hisahiko ; Retiounskaia, Marina ; Harvey, Robert J. ; Harvey, Kirsten ; O'Sullivan, Gregory A. ; Laube, Bodo ; Hülsmann, Swen ; Geiger, Jörg R. P. ; Betz, Heinrich :
Impaired GABAergic transmission and altered hippocampal synaptic plasticity in collybistin-deficient mice.
In: The EMBO journal, 26 (17) pp. 3888-99. ISSN 0261-4189
[Artikel], (2007)

Perret, P. ; Laube, Bodo ; Schemm, R. ; Betz, H. ; Goeldner, M. ; Foucaud, B. :
Affinity labeling of cysteine-mutants evidences contact residues in modeled receptor binding sites.
In: Journal of receptor and signal transduction research, 22 (1-4) pp. 345-56. ISSN 1079-9893
[Artikel], (2002)

S

Schumann, Tanja ; Grudzinska, Joanna ; Kuzmin, Dmitry ; Betz, Heinrich ; Laube, Bodo :
Binding-site mutations in the alpha1 subunit of the inhibitory glycine receptor convert the inhibitory metal ion Cu2+ into a positive modulator.
In: Neuropharmacology, 56 (1) pp. 310-7. ISSN 0028-3908
[Artikel], (2009)

Schüler, Thomas ; Mesic, Ivana ; Madry, Christian ; Bartholomäus, Ingo ; Laube, Bodo :
Formation of NR1/NR2 and NR1/NR3 heterodimers constitutes the initial step in N-methyl-D-aspartate receptor assembly.
In: The Journal of biological chemistry, 283 (1) pp. 37-46. ISSN 0021-9258
[Artikel], (2008)

Sadtler, Sven ; Laube, Bodo ; Lashub, Alhassan ; Nicke, Annette ; Betz, Heinrich ; Schmalzing, Günther :
A basic cluster determines topology of the cytoplasmic M3-M4 loop of the glycine receptor alpha1 subunit.
In: The Journal of biological chemistry, 278 (19) pp. 16782-90. ISSN 0021-9258
[Artikel], (2003)

T

Tamer, Ceyhun :
Role of Interdomain and Intersubunit Contacts for NMDA Receptor Function.
[Online-Edition: urn:nbn:de:tuda-tuprints-30984]
TU Darmstadt
[Dissertation], (2012)

U

Ultsch, A. ; Schuster, C. M. ; Laube, Bodo ; Betz, H. ; Schmitt, B. :
Glutamate receptors of Drosophila melanogaster. Primary structure of a putative NMDA receptor protein expressed in the head of the adult fly.
In: FEBS letters, 324 (2) pp. 171-7. ISSN 0014-5793
[Artikel], (1993)

Ultsch, A. ; Schuster, C. M. ; Laube, Bodo ; Schloss, P. ; Schmitt, B. ; Betz, H. :
Glutamate receptors of Drosophila melanogaster: cloning of a kainate-selective subunit expressed in the central nervous system.
In: Proceedings of the National Academy of Sciences of the United States of America, 89 (21) pp. 10484-8. ISSN 0027-8424
[Artikel], (1992)

V

von Spiczak, Sarah ; Lal, D. ; Reinthaler, E. M. ; Steiner, I. ; Nothnagel, M. ; Laube, Bodo ; Schwake, M. ; Hoffmann, P. ; Herms, S. ; Altmüller, J. ; Toliat, M. R. ; Thiele, H. ; Nürnberg, P. ; Wilhelm, C. ; Stephani, U. ; Helbig, I. ; Lerche, H. ; Zimprich, F. ; Neubauer, B. A. ; Biskup, S. ; Lemke, J. R. :
Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes.
In: Epilepsia, 54 p. 344. ISSN 0013-9580
[Artikel], (2013)

W

Wittekindt, B. ; Malany, S. ; Schemm, R. ; Otvos, L. ; Maccecchini, M. L. ; Laube, Bodo ; Betz, H. :
Point mutations identify the glutamate binding pocket of the N-methyl-D-aspartate receptor as major site of conantokin-G inhibition.
In: Neuropharmacology, 41 (6) pp. 753-61. ISSN 0028-3908
[Artikel], (2001)

Wittekindt, B. ; Betz, H. ; Laube, Bodo :
Subunit-dependent inhibition of recombinant rodent N-methyl-D-aspartate receptors by a HIV-1 glycoprotein 120 derived peptide.
In: Neuroscience letters, 280 (2) pp. 151-4. ISSN 0304-3940
[Artikel], (2000)

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