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Development of a sensor electronic for chemical and biological sensors based on ion conducting nanopores

Zhang, Xiaoyi (2016):
Development of a sensor electronic for chemical and biological sensors based on ion conducting nanopores.
TU Darmstadt, [Master Thesis]

Abstract

In this thesis, a portable sensor electronic is developed for chemical and biological sensors based on ion conducting nanopores. The developed electronic system is based on an Arduino board that is served as microcontroller. The voltage is supplied by a digital-to-analog converter with dual channels as well as an operational amplifier, which serves as a differential voltage subtractor. On the other side, the measured current is transformed to corresponding voltage by feedback method, which is composed of an operational amplifier, a 100 MOhm resistor and a 470 pF capacitor. The transformed voltage is measured by an analog-to-digital converter. The results are sent to the microcontroller, where the voltage is calculated and switched back to the corresponding ionic current. The electronic system supplies a voltage in the range of [-2, 2] V, and measures the resulting ionic current in the measurement range of [-20, 20] nA. The sensitivity of the current measurement is 10 pA. The electronic is combined with a Graphical User Interface on computer via USB cables. The measurement results can be transported to computer, saved as csv format and plotted as current/voltage-curves as well as current/time-curves in real time. The following figure and table shows the portable sensor electronic and its specifications. In addition, the electrodes, electrolyte and the nanopore membrane are abstracted as a lumped element model, which is used to evaluate the influence of the electrodes¡ position and area on the measured current.

Item Type: Master Thesis
Erschienen: 2016
Creators: Zhang, Xiaoyi
Title: Development of a sensor electronic for chemical and biological sensors based on ion conducting nanopores
Language: English
Abstract:

In this thesis, a portable sensor electronic is developed for chemical and biological sensors based on ion conducting nanopores. The developed electronic system is based on an Arduino board that is served as microcontroller. The voltage is supplied by a digital-to-analog converter with dual channels as well as an operational amplifier, which serves as a differential voltage subtractor. On the other side, the measured current is transformed to corresponding voltage by feedback method, which is composed of an operational amplifier, a 100 MOhm resistor and a 470 pF capacitor. The transformed voltage is measured by an analog-to-digital converter. The results are sent to the microcontroller, where the voltage is calculated and switched back to the corresponding ionic current. The electronic system supplies a voltage in the range of [-2, 2] V, and measures the resulting ionic current in the measurement range of [-20, 20] nA. The sensitivity of the current measurement is 10 pA. The electronic is combined with a Graphical User Interface on computer via USB cables. The measurement results can be transported to computer, saved as csv format and plotted as current/voltage-curves as well as current/time-curves in real time. The following figure and table shows the portable sensor electronic and its specifications. In addition, the electrodes, electrolyte and the nanopore membrane are abstracted as a lumped element model, which is used to evaluate the influence of the electrodes¡ position and area on the measured current.

Divisions: 18 Department of Electrical Engineering and Information Technology
18 Department of Electrical Engineering and Information Technology > Institute for Electromechanical Design
18 Department of Electrical Engineering and Information Technology > Institute for Electromechanical Design > Microtechnology and Electromechanical Systems
LOEWE
LOEWE > LOEWE-Schwerpunkte
LOEWE > LOEWE-Schwerpunkte > iNAPO – ion conducting NAnoPOres
Date Deposited: 13 Jan 2017 10:04
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