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Robust Nonlinear Causality Analysis of Non-Stationary Multivariate Physiological Time Series

Schäck, T. ; Muma, M. ; Feng, M. ; Guan, C. ; Zoubir, A. M. :
Robust Nonlinear Causality Analysis of Non-Stationary Multivariate Physiological Time Series.
In: IEEE Transactions on Biomedical Engineering, PP (99) p. 1. ISSN 0018-9294
[Artikel], (2017)

Kurzbeschreibung (Abstract)

Goal: An important research area in biomedical signal processing is that of quantifying the relationship between simultaneously observed time series and to reveal interactions between the signals. Since biomedical signals are potentially non-stationary and the measurements may contain outliers and artifacts, we introduce a robust time-varying generalized partial directed coherence (rTV-gPDC) function. Methods: The proposed method, which is based on a robust estimator of the timevarying autoregressive (TVAR) parameters, is capable of revealing directed interactions between signals. By definition, the rTV-gPDC only displays the linear relationships between the signals. We therefore suggest to approximate the residuals of the TVAR process, which potentially carry information about the nonlinear causality by a piece-wise linear time-varying moving-average (TVMA) model. Results: The performance of the proposed method is assessed via extensive simulations. To illustrate the method’s applicability to real-world problems, it is applied to a neurophysiological study that involves intracranial pressure (ICP), arterial blood pressure (ABP), and brain tissue oxygenation level (PtiO2) measurements. Conclusion and Significance: The rTV-gPDC reveals causal patterns that are in accordance with expected cardiosudoral meachanisms and potentially provides new insights regarding traumatic brain injuries (TBI). The rTV-gPDC is not restricted to the above problem but can be useful in revealing interactions in a broad range of applications.

Typ des Eintrags: Artikel
Erschienen: 2017
Autor(en): Schäck, T. ; Muma, M. ; Feng, M. ; Guan, C. ; Zoubir, A. M.
Titel: Robust Nonlinear Causality Analysis of Non-Stationary Multivariate Physiological Time Series
Sprache: Englisch
Kurzbeschreibung (Abstract):

Goal: An important research area in biomedical signal processing is that of quantifying the relationship between simultaneously observed time series and to reveal interactions between the signals. Since biomedical signals are potentially non-stationary and the measurements may contain outliers and artifacts, we introduce a robust time-varying generalized partial directed coherence (rTV-gPDC) function. Methods: The proposed method, which is based on a robust estimator of the timevarying autoregressive (TVAR) parameters, is capable of revealing directed interactions between signals. By definition, the rTV-gPDC only displays the linear relationships between the signals. We therefore suggest to approximate the residuals of the TVAR process, which potentially carry information about the nonlinear causality by a piece-wise linear time-varying moving-average (TVMA) model. Results: The performance of the proposed method is assessed via extensive simulations. To illustrate the method’s applicability to real-world problems, it is applied to a neurophysiological study that involves intracranial pressure (ICP), arterial blood pressure (ABP), and brain tissue oxygenation level (PtiO2) measurements. Conclusion and Significance: The rTV-gPDC reveals causal patterns that are in accordance with expected cardiosudoral meachanisms and potentially provides new insights regarding traumatic brain injuries (TBI). The rTV-gPDC is not restricted to the above problem but can be useful in revealing interactions in a broad range of applications.

Titel der Zeitschrift, Zeitung oder Schriftenreihe: IEEE Transactions on Biomedical Engineering
Band: PP
(Heft-)Nummer: 99
Freie Schlagworte: Biomedical measurement;Brain modeling;Coherence;Frequency-domain analysis;Mathematical model;Robustness;Time series analysis;Biomedical signal processing;Kalman filter;arterial blood pressure (ABP);connectivity analysis;directed coherence;generalized partial directed coherence (gPDC);intracranial pressure (ICP);multivariate autoregressive modeling;partial directed coherence (PDC);time-varying autoregressive (TVAR);time-varying moving-average (TVMA);traumatic brain injuries (TBI)
Fachbereich(e)/-gebiet(e): 18 Fachbereich Elektrotechnik und Informationstechnik > Institut für Nachrichtentechnik > Signalverarbeitung
18 Fachbereich Elektrotechnik und Informationstechnik > Institut für Nachrichtentechnik
18 Fachbereich Elektrotechnik und Informationstechnik
Hinterlegungsdatum: 14 Dez 2016 12:51
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