Unger, M. ; Lee, S.-S. ; Peter, M. ; Koeppl, H. (2011)
Pulse Width Modulation of Liquid Flows.
15th International Conference on Miniaturized Systems for Chemistry and Life Sciences.
Konferenzveröffentlichung, Bibliographie
Kurzbeschreibung (Abstract)
Advanced methods for live cell analysis help to understand fundamental processes within a cell. We propose a method to generate specific input stimuli that are essentially needed to get insights to dynamic cellular behavior. By Pulse-Width- Modulation (PWM) of liquid flows, we offer a fast and reliable way to generate temporal profiles of media concentration that can be combined with other microfluidic devices. Its functionality is demonstrated in experiments of salt concentration ramping, which is of high interest and biological relevance for maintaining activation of the Mitogen Activated Protein Kinase (MAPK) Hog1 in the High Osmolarity Glycerol (HOG) pathway.
| Typ des Eintrags: | Konferenzveröffentlichung |
|---|---|
| Erschienen: | 2011 |
| Autor(en): | Unger, M. ; Lee, S.-S. ; Peter, M. ; Koeppl, H. |
| Art des Eintrags: | Bibliographie |
| Titel: | Pulse Width Modulation of Liquid Flows |
| Sprache: | Deutsch |
| Publikationsjahr: | 2011 |
| Ort: | San Diego, CA |
| Verlag: | Chemical and Biological Microsystems Society |
| Veranstaltungstitel: | 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
| URL / URN: | http://e-citations.ethbib.ethz.ch/view/pub:68788 |
| Kurzbeschreibung (Abstract): | Advanced methods for live cell analysis help to understand fundamental processes within a cell. We propose a method to generate specific input stimuli that are essentially needed to get insights to dynamic cellular behavior. By Pulse-Width- Modulation (PWM) of liquid flows, we offer a fast and reliable way to generate temporal profiles of media concentration that can be combined with other microfluidic devices. Its functionality is demonstrated in experiments of salt concentration ramping, which is of high interest and biological relevance for maintaining activation of the Mitogen Activated Protein Kinase (MAPK) Hog1 in the High Osmolarity Glycerol (HOG) pathway. |
| Freie Schlagworte: | Concentration Ramping,Pulse Width Modulation,Signaling Pathway |
| Fachbereich(e)/-gebiet(e): | 18 Fachbereich Elektrotechnik und Informationstechnik 18 Fachbereich Elektrotechnik und Informationstechnik > Institut für Nachrichtentechnik > Bioinspirierte Kommunikationssysteme 18 Fachbereich Elektrotechnik und Informationstechnik > Institut für Nachrichtentechnik |
| Hinterlegungsdatum: | 04 Apr 2014 11:41 |
| Letzte Änderung: | 23 Sep 2021 14:32 |
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