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Pulse Width Modulation of Liquid Flows

Unger, M. and Lee, S.-S. and Peter, M. and Koeppl, H. (2011):
Pulse Width Modulation of Liquid Flows.
San Diego, CA, Chemical and Biological Microsystems Society, In: 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences, [Online-Edition: http://e-citations.ethbib.ethz.ch/view/pub:68788],
[Conference or Workshop Item]

Abstract

Advanced methods for live cell analysis help to understand fundamental processes within a cell. We propose a method to generate specific input stimuli that are essentially needed to get insights to dynamic cellular behavior. By Pulse-Width- Modulation (PWM) of liquid flows, we offer a fast and reliable way to generate temporal profiles of media concentration that can be combined with other microfluidic devices. Its functionality is demonstrated in experiments of salt concentration ramping, which is of high interest and biological relevance for maintaining activation of the Mitogen Activated Protein Kinase (MAPK) Hog1 in the High Osmolarity Glycerol (HOG) pathway.

Item Type: Conference or Workshop Item
Erschienen: 2011
Creators: Unger, M. and Lee, S.-S. and Peter, M. and Koeppl, H.
Title: Pulse Width Modulation of Liquid Flows
Language: German
Abstract:

Advanced methods for live cell analysis help to understand fundamental processes within a cell. We propose a method to generate specific input stimuli that are essentially needed to get insights to dynamic cellular behavior. By Pulse-Width- Modulation (PWM) of liquid flows, we offer a fast and reliable way to generate temporal profiles of media concentration that can be combined with other microfluidic devices. Its functionality is demonstrated in experiments of salt concentration ramping, which is of high interest and biological relevance for maintaining activation of the Mitogen Activated Protein Kinase (MAPK) Hog1 in the High Osmolarity Glycerol (HOG) pathway.

Place of Publication: San Diego, CA
Publisher: Chemical and Biological Microsystems Society
Uncontrolled Keywords: Concentration Ramping,Pulse Width Modulation,Signaling Pathway
Divisions: 18 Department of Electrical Engineering and Information Technology > Institute for Telecommunications > Bioinspired Communication Systems
18 Department of Electrical Engineering and Information Technology
18 Department of Electrical Engineering and Information Technology > Institute for Telecommunications
Event Title: 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Date Deposited: 04 Apr 2014 11:41
Official URL: http://e-citations.ethbib.ethz.ch/view/pub:68788
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