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A Statistical analysis of receptor

Koeppl, H. and Schumacher, L. and Danos, V. (2009):
A Statistical analysis of receptor.
Aarhus, Denmark, In: Proceedings of the International Workshop on Computtional Systmes Biology (WCSB), [Conference or Workshop Item]

Abstract

We address the problem of phase transitions in random site graphs. Such graphs were recently proposed as more useful abstractions of proteins and their network of interactions than standard graphs. A set of binding reactions between proteins give rise to the stochastic assembly of protein complexes. We use a rule-based language to represent and simulate such systems. Based on methods from statistical physics we investigate the dependency of the asymptotic size distribution of such complexes with respect to the site configuration and binding affinities of and between proteins, respectively. In particular we discuss a liquidity index of such abstract protein networks and apply it to the problem of chemoreceptor clustering in E. coli.

Item Type: Conference or Workshop Item
Erschienen: 2009
Creators: Koeppl, H. and Schumacher, L. and Danos, V.
Title: A Statistical analysis of receptor
Language: English
Abstract:

We address the problem of phase transitions in random site graphs. Such graphs were recently proposed as more useful abstractions of proteins and their network of interactions than standard graphs. A set of binding reactions between proteins give rise to the stochastic assembly of protein complexes. We use a rule-based language to represent and simulate such systems. Based on methods from statistical physics we investigate the dependency of the asymptotic size distribution of such complexes with respect to the site configuration and binding affinities of and between proteins, respectively. In particular we discuss a liquidity index of such abstract protein networks and apply it to the problem of chemoreceptor clustering in E. coli.

Place of Publication: Aarhus, Denmark
Divisions: 18 Department of Electrical Engineering and Information Technology > Institute for Telecommunications > Bioinspired Communication Systems
18 Department of Electrical Engineering and Information Technology
18 Department of Electrical Engineering and Information Technology > Institute for Telecommunications
Event Title: Proceedings of the International Workshop on Computtional Systmes Biology (WCSB)
Date Deposited: 04 Apr 2014 12:34
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