Weigand, Julia E. ; Suess, Beatrix (2009)
Aptamers and riboswitches: perspectives in biotechnology.
In: Applied microbiology and biotechnology, 85 (2)
Artikel, Bibliographie
Kurzbeschreibung (Abstract)
Aptamers are short, single stranded nucleic acids which bind a wide range of different ligands with extraordinary high binding affinity and specificity. The steadily increasing number of aptamers is accompanied by an expanding range of applications in biotechnology. We will describe new developments in the field including the use of aptamers for conditional gene regulation and as biosensors. In addition, we will discuss the potential of aptamers as tags to visualize RNA and protein distribution in living cells and as therapeutics. Furthermore, we will consider biotechnological applications of riboswitches for gene regulation and as drug target.
| Typ des Eintrags: | Artikel |
|---|---|
| Erschienen: | 2009 |
| Autor(en): | Weigand, Julia E. ; Suess, Beatrix |
| Art des Eintrags: | Bibliographie |
| Titel: | Aptamers and riboswitches: perspectives in biotechnology. |
| Sprache: | Englisch |
| Publikationsjahr: | 2009 |
| Titel der Zeitschrift, Zeitung oder Schriftenreihe: | Applied microbiology and biotechnology |
| Jahrgang/Volume einer Zeitschrift: | 85 |
| (Heft-)Nummer: | 2 |
| Kurzbeschreibung (Abstract): | Aptamers are short, single stranded nucleic acids which bind a wide range of different ligands with extraordinary high binding affinity and specificity. The steadily increasing number of aptamers is accompanied by an expanding range of applications in biotechnology. We will describe new developments in the field including the use of aptamers for conditional gene regulation and as biosensors. In addition, we will discuss the potential of aptamers as tags to visualize RNA and protein distribution in living cells and as therapeutics. Furthermore, we will consider biotechnological applications of riboswitches for gene regulation and as drug target. |
| Fachbereich(e)/-gebiet(e): | 10 Fachbereich Biologie 10 Fachbereich Biologie > Synthetic Genetic Circuits (2020 umbenannt in "Synthetic RNA biology") 10 Fachbereich Biologie > RNA Biochemie |
| Hinterlegungsdatum: | 22 Feb 2012 10:26 |
| Letzte Änderung: | 06 Nov 2020 07:20 |
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