TU Darmstadt / ULB / TUbiblio

Conservation of amino acid transporters in fungi, plants and animals.

Wipf, Daniel and Ludewig, Uwe and Tegeder, Mechthild and Rentsch, Doris and Koch, Wolfgang and Frommer, Wolf B. :
Conservation of amino acid transporters in fungi, plants and animals.
In: Trends in biochemical sciences, 27 (3) pp. 139-47. ISSN 0968-0004
[Article] , (2002)

Abstract

When comparing the transporters of three completely sequenced eukaryotic genomes--Saccharomyces cerevisiae, Arabidopsis thaliana and Homo sapiens--transporter types can be distinguished according to phylogeny, substrate spectrum, transport mechanism and cell specificity. The known amino acid transporters belong to five different superfamilies. Two preferentially Na(+)-coupled transporter superfamilies are not represented in the yeast and Arabidopsis genomes, whereas the other three groups, which often function as H(+)-coupled systems, have members in all investigated genomes. Additional superfamilies exist for organellar transport, including mitochondrial and plastidic carriers. When used in combination with phylogenetic analyses, functional comparison might aid our prediction of physiological functions for related but uncharacterized open reading frames.

Item Type: Article
Erschienen: 2002
Creators: Wipf, Daniel and Ludewig, Uwe and Tegeder, Mechthild and Rentsch, Doris and Koch, Wolfgang and Frommer, Wolf B.
Title: Conservation of amino acid transporters in fungi, plants and animals.
Language: English
Abstract:

When comparing the transporters of three completely sequenced eukaryotic genomes--Saccharomyces cerevisiae, Arabidopsis thaliana and Homo sapiens--transporter types can be distinguished according to phylogeny, substrate spectrum, transport mechanism and cell specificity. The known amino acid transporters belong to five different superfamilies. Two preferentially Na(+)-coupled transporter superfamilies are not represented in the yeast and Arabidopsis genomes, whereas the other three groups, which often function as H(+)-coupled systems, have members in all investigated genomes. Additional superfamilies exist for organellar transport, including mitochondrial and plastidic carriers. When used in combination with phylogenetic analyses, functional comparison might aid our prediction of physiological functions for related but uncharacterized open reading frames.

Journal or Publication Title: Trends in biochemical sciences
Volume: 27
Number: 3
Divisions: 10 Department of Biology > Plant Nutrition and Biomass
?? fb10_botanik ??
10 Department of Biology
Date Deposited: 17 Mar 2010 15:45
Export:

Optionen (nur für Redakteure)

View Item View Item