Hessinger, Carolin ; Schüßler, Martin ; Klos, Sabrina ; Kochanek, Markus ; Jakoby, Rolf (2022)
Numerical Optimization of an Open-Ended Coaxial Slot Applicator for the Detection and Microwave Ablation of Tumors.
In: Biology, 2022, 10 (9)
doi: 10.26083/tuprints-00019981
Artikel, Zweitveröffentlichung, Verlagsversion
Kurzbeschreibung (Abstract)
A multiobjective optimization method for a dual-mode microwave applicator is proposed. Dual-modality means that microwaves are used apart from the treatment, and also for the monitoring of the microwave ablation intervention. (1) The use of computational models to develop and improve microwave ablation applicator geometries is essential for further advances in this field. (2) Numerical electromagnetic–thermal coupled simulation models are used to analyze the performance of the dual-mode applicator in liver tissue; the sensitivity evaluation of the dual-mode applicator’s sensing mode constrains the set of optimal solutions. (3) Three Pareto-optimal design parameter sets are derived that are optimal in terms of applicator efficiency as well as volume and sphericity of the ablation zone. The resulting designs of the dual-mode applicator provide a suitable sensitivity to distinguish between healthy and tumorous liver tissue. (4) The optimized designs are presented and numerically characterized. An improvement on the performance of previously proposed dual-mode applicator designs is achieved. The multiphysical simulation model of electromagnetic and thermal properties of the applicator is applicable for future comprehensive design procedures.
| Typ des Eintrags: | Artikel | ||||
|---|---|---|---|---|---|
| Erschienen: | 2022 | ||||
| Autor(en): | Hessinger, Carolin ; Schüßler, Martin ; Klos, Sabrina ; Kochanek, Markus ; Jakoby, Rolf | ||||
| Art des Eintrags: | Zweitveröffentlichung | ||||
| Titel: | Numerical Optimization of an Open-Ended Coaxial Slot Applicator for the Detection and Microwave Ablation of Tumors | ||||
| Sprache: | Englisch | ||||
| Publikationsjahr: | 2022 | ||||
| Publikationsdatum der Erstveröffentlichung: | 2022 | ||||
| Verlag: | MDPI | ||||
| Titel der Zeitschrift, Zeitung oder Schriftenreihe: | Biology | ||||
| Jahrgang/Volume einer Zeitschrift: | 10 | ||||
| (Heft-)Nummer: | 9 | ||||
| Kollation: | 12 Seiten | ||||
| DOI: | 10.26083/tuprints-00019981 | ||||
| URL / URN: | https://tuprints.ulb.tu-darmstadt.de/19981 | ||||
| Zugehörige Links: | |||||
| Herkunft: | Zweitveröffentlichung DeepGreen | ||||
| Kurzbeschreibung (Abstract): | A multiobjective optimization method for a dual-mode microwave applicator is proposed. Dual-modality means that microwaves are used apart from the treatment, and also for the monitoring of the microwave ablation intervention. (1) The use of computational models to develop and improve microwave ablation applicator geometries is essential for further advances in this field. (2) Numerical electromagnetic–thermal coupled simulation models are used to analyze the performance of the dual-mode applicator in liver tissue; the sensitivity evaluation of the dual-mode applicator’s sensing mode constrains the set of optimal solutions. (3) Three Pareto-optimal design parameter sets are derived that are optimal in terms of applicator efficiency as well as volume and sphericity of the ablation zone. The resulting designs of the dual-mode applicator provide a suitable sensitivity to distinguish between healthy and tumorous liver tissue. (4) The optimized designs are presented and numerically characterized. An improvement on the performance of previously proposed dual-mode applicator designs is achieved. The multiphysical simulation model of electromagnetic and thermal properties of the applicator is applicable for future comprehensive design procedures. |
||||
| Alternatives oder übersetztes Abstract: |
|
||||
| Freie Schlagworte: | microwave ablation, microwave applicator, multiobjective optimization | ||||
| Status: | Verlagsversion | ||||
| URN: | urn:nbn:de:tuda-tuprints-199810 | ||||
| Sachgruppe der Dewey Dezimalklassifikatin (DDC): | 500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie 600 Technik, Medizin, angewandte Wissenschaften > 620 Ingenieurwissenschaften und Maschinenbau |
||||
| Fachbereich(e)/-gebiet(e): | 18 Fachbereich Elektrotechnik und Informationstechnik 18 Fachbereich Elektrotechnik und Informationstechnik > Institut für Mikrowellentechnik und Photonik (IMP) > Mikrowellentechnik 18 Fachbereich Elektrotechnik und Informationstechnik > Institut für Mikrowellentechnik und Photonik (IMP) 18 Fachbereich Elektrotechnik und Informationstechnik > Institut für Nachrichtentechnik 18 Fachbereich Elektrotechnik und Informationstechnik > Institut für Nachrichtentechnik > Kommunikationstechnik |
||||
| Hinterlegungsdatum: | 02 Mai 2022 11:51 | ||||
| Letzte Änderung: | 15 Sep 2022 09:39 | ||||
| PPN: | |||||
| Zugehörige Links: | |||||
| Export: | |||||
| Suche nach Titel in: | TUfind oder in Google | ||||
 |
Frage zum Eintrag |
Optionen (nur für Redakteure)
 |
Redaktionelle Details anzeigen |
Drucken
Impressum