Han, Haoya ; Li, Li ; Tian, Yuchuan ; Wang, Yunwei ; Ye, Zhishuang ; Yang, Qingsong ; Wang, Yiming ; Klitzing, Regine von ; Guo, Xuhong (2021)
Spherical polyelectrolyte nanogels as templates to prepare hollow silica nanocarriers: observation by small angle X-ray scattering and TEM.
In: RSC Advances, 7 (76)
doi: 10.26083/tuprints-00019059
Artikel, Zweitveröffentlichung, Verlagsversion
Kurzbeschreibung (Abstract)
Hollow silica nanoparticles were prepared through generating a silica layer in spherical polyelectrolyte nanogels (SPN), which consisted of a solid core of polystyrene (PS) and a shell of crosslinked poly(acrylic acid) (PAA), followed by removing the PS core via solvent dissolution. Small angle X-ray scattering (SAXS) in combination with TEM were employed to observe SPN, silica–polymer composite, and hollow silica nanoparticles. It was confirmed that SAXS is a powerful method to monitor the generation of silica layer in SPN. The density and thickness of generated silica layer in SPN were found to be tunable by controlling the crosslinking density of the templates. The porous structure and pH sensitivity of silica layer allowed the obtained hollow silica to be ideal carriers for controlled drug delivery.
| Typ des Eintrags: | Artikel |
|---|---|
| Erschienen: | 2021 |
| Autor(en): | Han, Haoya ; Li, Li ; Tian, Yuchuan ; Wang, Yunwei ; Ye, Zhishuang ; Yang, Qingsong ; Wang, Yiming ; Klitzing, Regine von ; Guo, Xuhong |
| Art des Eintrags: | Zweitveröffentlichung |
| Titel: | Spherical polyelectrolyte nanogels as templates to prepare hollow silica nanocarriers: observation by small angle X-ray scattering and TEM |
| Sprache: | Englisch |
| Publikationsjahr: | 2021 |
| Verlag: | Royal Society of Chemistry |
| Titel der Zeitschrift, Zeitung oder Schriftenreihe: | RSC Advances |
| Jahrgang/Volume einer Zeitschrift: | 7 |
| (Heft-)Nummer: | 76 |
| DOI: | 10.26083/tuprints-00019059 |
| URL / URN: | https://tuprints.ulb.tu-darmstadt.de/19059 |
| Zugehörige Links: | |
| Herkunft: | Zweitveröffentlichungsservice |
| Kurzbeschreibung (Abstract): | Hollow silica nanoparticles were prepared through generating a silica layer in spherical polyelectrolyte nanogels (SPN), which consisted of a solid core of polystyrene (PS) and a shell of crosslinked poly(acrylic acid) (PAA), followed by removing the PS core via solvent dissolution. Small angle X-ray scattering (SAXS) in combination with TEM were employed to observe SPN, silica–polymer composite, and hollow silica nanoparticles. It was confirmed that SAXS is a powerful method to monitor the generation of silica layer in SPN. The density and thickness of generated silica layer in SPN were found to be tunable by controlling the crosslinking density of the templates. The porous structure and pH sensitivity of silica layer allowed the obtained hollow silica to be ideal carriers for controlled drug delivery. |
| Status: | Verlagsversion |
| URN: | urn:nbn:de:tuda-tuprints-190597 |
| Sachgruppe der Dewey Dezimalklassifikatin (DDC): | 500 Naturwissenschaften und Mathematik > 530 Physik 500 Naturwissenschaften und Mathematik > 540 Chemie |
| Fachbereich(e)/-gebiet(e): | Profilbereiche Profilbereiche > Thermo-Fluids & Interfaces 05 Fachbereich Physik 05 Fachbereich Physik > Institut für Physik Kondensierter Materie (IPKM) |
| Hinterlegungsdatum: | 06 Sep 2021 12:23 |
| Letzte Änderung: | 20 Sep 2021 07:40 |
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