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Review: Silicon oxycarbide based materials for biomedical applications

Arango-Ospina, Marcela and Xie, Fangtong and Gonzalo-Juan, Isabel and Riedel, Ralf and Ionescu, Emanuel and Boccaccini, Aldo R. (2020):
Review: Silicon oxycarbide based materials for biomedical applications.
In: Applied Materials Today, 18, p. 100482. Elsevier, ISSN 2352-9407,
DOI: https:doi.org/10.1016/j.apmt.2019.100482,
[Article]

Abstract

Silicon oxycarbide (SiOC) based materials are of interest due to their unique properties, including high-temperature resistance, mechanical strength, chemical durability and corrosion resistance. The versatility of the silicon oxycarbide chemistry allows the modification of properties for different fields. In the last decade, attention has been paid to the potential use of SiOC materials in biomedical applications. Surface functionalization of SiOC is a promising approach to create efficient and controllable drug delivery systems with adequate molecule adsorption and release kinetics. The analysis of the literature reveals that silicon oxycarbides have also potential applications as protective biocompatible coatings, for example in blood-contact devices. Additionally, by incorporating metallic ions (i.e. Ca2+, Mg2+, Ag+) in the material network structure, promising antibacterial properties and bioactive behavior have been observed despite the high network connectivity values compared to silicate bioactive glasses. This review covers studies which have reported the use of silicon oxycarbide based materials for biomedical applications. Advances in the evaluation of biocompatibility, bioactivity, surface functionalization and antibacterial effects are discussed in detail, highlighting advantages and limitations of SiOC systems in the biomedical field. (C) 2019 Elsevier Ltd. All rights reserved.

Item Type: Article
Erschienen: 2020
Creators: Arango-Ospina, Marcela and Xie, Fangtong and Gonzalo-Juan, Isabel and Riedel, Ralf and Ionescu, Emanuel and Boccaccini, Aldo R.
Title: Review: Silicon oxycarbide based materials for biomedical applications
Language: English
Abstract:

Silicon oxycarbide (SiOC) based materials are of interest due to their unique properties, including high-temperature resistance, mechanical strength, chemical durability and corrosion resistance. The versatility of the silicon oxycarbide chemistry allows the modification of properties for different fields. In the last decade, attention has been paid to the potential use of SiOC materials in biomedical applications. Surface functionalization of SiOC is a promising approach to create efficient and controllable drug delivery systems with adequate molecule adsorption and release kinetics. The analysis of the literature reveals that silicon oxycarbides have also potential applications as protective biocompatible coatings, for example in blood-contact devices. Additionally, by incorporating metallic ions (i.e. Ca2+, Mg2+, Ag+) in the material network structure, promising antibacterial properties and bioactive behavior have been observed despite the high network connectivity values compared to silicate bioactive glasses. This review covers studies which have reported the use of silicon oxycarbide based materials for biomedical applications. Advances in the evaluation of biocompatibility, bioactivity, surface functionalization and antibacterial effects are discussed in detail, highlighting advantages and limitations of SiOC systems in the biomedical field. (C) 2019 Elsevier Ltd. All rights reserved.

Journal or Publication Title: Applied Materials Today
Journal volume: 18
Publisher: Elsevier
Uncontrolled Keywords: Silicon oxycarbide; Biocompatibility; Cytotoxicity; Bioactive glass; Polymer-derived ceramic; Coating; Polymer-Derived Ceramics; Electrical-Conductivity; Surface-Roughness; Bioactive Glasses; Cytotoxicity; Nanocomposites; Titanium; Energy; Microelectrodes; Energetics
Divisions: 11 Department of Materials and Earth Sciences
11 Department of Materials and Earth Sciences > Material Science
11 Department of Materials and Earth Sciences > Material Science > Dispersive Solids
Date Deposited: 12 Jun 2020 06:29
DOI: https:doi.org/10.1016/j.apmt.2019.100482
Official URL: https://www.sciencedirect.com/science/article/pii/S235294071...
Projects: German Research Foundation (DFG), Grant Numbers 317658328 (IO 64/9-1), 317658328 (BO1191/15-1), EUCOST Action Smart Inorganic Polymers, Grant Number CM 1302, German Research Foundation (DFG), Grant Number IO 64/14-1
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