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Dielectric Contrast Between Normal and Tumor Ex-Vivo Human Liver Tissue

Hessinger Nee Reimann, Carolin and Jakoby, Rolf and Bazrafshan, Babak and Hübner, Frank and Schmidt, Sönke and Schüler, Martin and Panahi, Bita and Kaltenbach, Benjamin and Polkowski, Christoph and Vogl, Thomas J. (2019):
Dielectric Contrast Between Normal and Tumor Ex-Vivo Human Liver Tissue.
In: IEEE Access, 7. IEEE, pp. 164113-164119, e-ISSN 2169-3536,
DOI: 10.25534/tuprints-00009679,
[Online-Edition: https://tuprints.ulb.tu-darmstadt.de/9679],
Secondary publishing via sponsored Golden Open Access, [Article]

Abstract

Microwave ablation (MWA) is a promising treatment option for patients suffering from liver cancer utilizing electromagnetic wave heating within the targeted tissue at microwave frequencies. Knowledge about the dielectric properties of the targeted tissues is essential for the design of recent MWA systems by including treatment monitoring possibilities. This work focuses on the evaluation of the patient-specific dielectric contrast between healthy and diseased liver parts at discrete frequencies at 2.45 GHz and 5.8 GHz, as well as a broadband data analysis. Measurements yield a frequency-dependent dielectric contrast with local maxima for each patient. Due to large variations between the dielectric properties of the patients, the need for individual thresholds can be derived to distinguish between healthy and malignant tissue.

Item Type: Article
Erschienen: 2019
Creators: Hessinger Nee Reimann, Carolin and Jakoby, Rolf and Bazrafshan, Babak and Hübner, Frank and Schmidt, Sönke and Schüler, Martin and Panahi, Bita and Kaltenbach, Benjamin and Polkowski, Christoph and Vogl, Thomas J.
Title: Dielectric Contrast Between Normal and Tumor Ex-Vivo Human Liver Tissue
Language: English
Abstract:

Microwave ablation (MWA) is a promising treatment option for patients suffering from liver cancer utilizing electromagnetic wave heating within the targeted tissue at microwave frequencies. Knowledge about the dielectric properties of the targeted tissues is essential for the design of recent MWA systems by including treatment monitoring possibilities. This work focuses on the evaluation of the patient-specific dielectric contrast between healthy and diseased liver parts at discrete frequencies at 2.45 GHz and 5.8 GHz, as well as a broadband data analysis. Measurements yield a frequency-dependent dielectric contrast with local maxima for each patient. Due to large variations between the dielectric properties of the patients, the need for individual thresholds can be derived to distinguish between healthy and malignant tissue.

Journal or Publication Title: IEEE Access
Publisher: IEEE
Divisions: 18 Department of Electrical Engineering and Information Technology
18 Department of Electrical Engineering and Information Technology > Institute for Microwave Engineering and Photonics
Date Deposited: 15 Dec 2019 20:55
DOI: 10.25534/tuprints-00009679
Official URL: https://tuprints.ulb.tu-darmstadt.de/9679
URN: urn:nbn:de:tuda-tuprints-96794
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