Saul, Meike J. ; Emmerich, Anne C. ; Steinhilber, Dieter ; Suess, Beatrix (2019)
Regulation of Eicosanoid Pathways by MicroRNAs.
In: Frontiers in pharmacology, 10
doi: 10.3389/fphar.2019.00824
Artikel, Bibliographie
Kurzbeschreibung (Abstract)
Over the last years, many microRNAs (miRNAs) have been identified that regulate the formation of bioactive lipid mediators such as prostanoids and leukotrienes. Many of these miRNAs are involved in complex regulatory circuits necessary for the fine-tuning of biological functions including inflammatory processes or cell growth. A better understanding of these networks will contribute to the development of novel therapeutic strategies for the treatment of inflammatory diseases and cancer. In this review, we provide an overview of the current knowledge of miRNA regulation in eicosanoid pathways with special focus on novel miRNA functions and regulatory circuits of leukotriene and prostaglandin biosynthesis.
| Typ des Eintrags: | Artikel |
|---|---|
| Erschienen: | 2019 |
| Autor(en): | Saul, Meike J. ; Emmerich, Anne C. ; Steinhilber, Dieter ; Suess, Beatrix |
| Art des Eintrags: | Bibliographie |
| Titel: | Regulation of Eicosanoid Pathways by MicroRNAs. |
| Sprache: | Englisch |
| Publikationsjahr: | 19 Juli 2019 |
| Titel der Zeitschrift, Zeitung oder Schriftenreihe: | Frontiers in pharmacology |
| Jahrgang/Volume einer Zeitschrift: | 10 |
| DOI: | 10.3389/fphar.2019.00824 |
| Kurzbeschreibung (Abstract): | Over the last years, many microRNAs (miRNAs) have been identified that regulate the formation of bioactive lipid mediators such as prostanoids and leukotrienes. Many of these miRNAs are involved in complex regulatory circuits necessary for the fine-tuning of biological functions including inflammatory processes or cell growth. A better understanding of these networks will contribute to the development of novel therapeutic strategies for the treatment of inflammatory diseases and cancer. In this review, we provide an overview of the current knowledge of miRNA regulation in eicosanoid pathways with special focus on novel miRNA functions and regulatory circuits of leukotriene and prostaglandin biosynthesis. |
| ID-Nummer: | pmid:31379585 |
| Fachbereich(e)/-gebiet(e): | 10 Fachbereich Biologie 10 Fachbereich Biologie > Synthetic Genetic Circuits (2020 umbenannt in "Synthetic RNA biology") |
| Hinterlegungsdatum: | 26 Aug 2019 09:27 |
| Letzte Änderung: | 26 Aug 2019 09:27 |
| PPN: | |
| Export: | |
| Suche nach Titel in: | TUfind oder in Google |
 |
Frage zum Eintrag |
Optionen (nur für Redakteure)
 |
Redaktionelle Details anzeigen |
Drucken
Impressum