TU Darmstadt / ULB / TUbiblio

A Patient-Specific Foot Model for the Estimate of Ankle Joint Forces in Patients with Juvenile Idiopathic Arthritis

Prinold, Joe A. I. ; Mazzà, Claudia ; Di Marco, Roberto ; Hannah, Iain ; Malattia, Clara ; Magni-Manzoni, Silvia ; Petrarca, Maurizio ; Ronchetti, Anna B. ; Tanturri De Horatio, Laura ; Dijkhuizen, Pieter E. H. van ; Wesarg, Stefan ; Viceconti, Marco (2016)
A Patient-Specific Foot Model for the Estimate of Ankle Joint Forces in Patients with Juvenile Idiopathic Arthritis.
In: Annals of Biomedical Engineering, 44 (1)
doi: 10.1007/s10439-015-1451-z
Artikel, Bibliographie

Kurzbeschreibung (Abstract)

Juvenile idiopathic arthritis (JIA) is the leading cause of childhood disability from a musculoskeletal disorder. It generally affects large joints such as the knee and the ankle, often causing structural damage. Different factors contribute to the damage onset, including altered joint loading and other mechanical factors, associated with pain and inflammation. The prediction of patients' joint loading can hence be a valuable tool in understanding the disease mechanisms involved in structural damage progression. A number of lower-limb musculoskeletal models have been proposed to analyse the hip and knee joints, but juvenile models of the foot are still lacking. This paper presents a modelling pipeline that allows the creation of juvenile patient-specific models starting from lower limb kinematics and foot and ankle MRI data. This pipeline has been applied to data from three children with JIA and the importance of patient-specific parameters and modelling assumptions has been tested in a sensitivity analysis focused on the variation of the joint reaction forces. This analysis highlighted the criticality of patient-specific definition of the ankle joint axes and location of the Achilles tendon insertions. Patient-specific detection of the Tibialis Anterior, Tibialis Posterior, and Peroneus Longus origins and insertions were also shown to be important.

Typ des Eintrags: Artikel
Erschienen: 2016
Autor(en): Prinold, Joe A. I. ; Mazzà, Claudia ; Di Marco, Roberto ; Hannah, Iain ; Malattia, Clara ; Magni-Manzoni, Silvia ; Petrarca, Maurizio ; Ronchetti, Anna B. ; Tanturri De Horatio, Laura ; Dijkhuizen, Pieter E. H. van ; Wesarg, Stefan ; Viceconti, Marco
Art des Eintrags: Bibliographie
Titel: A Patient-Specific Foot Model for the Estimate of Ankle Joint Forces in Patients with Juvenile Idiopathic Arthritis
Sprache: Englisch
Publikationsjahr: 2016
Titel der Zeitschrift, Zeitung oder Schriftenreihe: Annals of Biomedical Engineering
Jahrgang/Volume einer Zeitschrift: 44
(Heft-)Nummer: 1
DOI: 10.1007/s10439-015-1451-z
Kurzbeschreibung (Abstract):

Juvenile idiopathic arthritis (JIA) is the leading cause of childhood disability from a musculoskeletal disorder. It generally affects large joints such as the knee and the ankle, often causing structural damage. Different factors contribute to the damage onset, including altered joint loading and other mechanical factors, associated with pain and inflammation. The prediction of patients' joint loading can hence be a valuable tool in understanding the disease mechanisms involved in structural damage progression. A number of lower-limb musculoskeletal models have been proposed to analyse the hip and knee joints, but juvenile models of the foot are still lacking. This paper presents a modelling pipeline that allows the creation of juvenile patient-specific models starting from lower limb kinematics and foot and ankle MRI data. This pipeline has been applied to data from three children with JIA and the importance of patient-specific parameters and modelling assumptions has been tested in a sensitivity analysis focused on the variation of the joint reaction forces. This analysis highlighted the criticality of patient-specific definition of the ankle joint axes and location of the Achilles tendon insertions. Patient-specific detection of the Tibialis Anterior, Tibialis Posterior, and Peroneus Longus origins and insertions were also shown to be important.

Freie Schlagworte: Guiding Theme: Individual Health, Research Area: Computer graphics (CG), Research Area: (Interactive) simulation (SIM), Research Area: Modeling (MOD), Magnetic resonance imaging (MRI), Marker based tracking, Computational anatomy
Fachbereich(e)/-gebiet(e): 20 Fachbereich Informatik
20 Fachbereich Informatik > Mathematisches und angewandtes Visual Computing
Hinterlegungsdatum: 03 Mai 2019 07:14
Letzte Änderung: 23 Jul 2021 12:15
PPN:
Export:
Suche nach Titel in: TUfind oder in Google
Frage zum Eintrag Frage zum Eintrag

Optionen (nur für Redakteure)
Redaktionelle Details anzeigen Redaktionelle Details anzeigen