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Single-portal-phase Low-tube-voltage Dual-energy CT for Short-term Follow-up of Acute Pancreatitis: Evaluation of CT Severity Index, Interobserver Agreement and Radiation Dose

Wichmann, Julian L. ; Majenka, Pavel ; Beeres, Martin ; Kromen, Wolfgang ; Schulz, Boris ; Wesarg, Stefan ; Bauer, Ralf W. ; Kerl, J. Matthias ; Gruber-Rouh, Tatjana ; Hammerstingl, Renate ; Vogl, Thomas J. ; Lehnert, Thomas (2014)
Single-portal-phase Low-tube-voltage Dual-energy CT for Short-term Follow-up of Acute Pancreatitis: Evaluation of CT Severity Index, Interobserver Agreement and Radiation Dose.
In: European Radiology, 24 (11)
doi: 10.1007/s00330-014-3300-0
Artikel, Bibliographie

Kurzbeschreibung (Abstract)

Objectives: To intra-individually compare single-portal-phase low-tube-voltage (100-kVp) computed tomography (CT) with 120-kVp images for short-term follow-up assessment of CT severity index (CTSI) of acute pancreatitis, interobserver agreement and radiation dose. Methods: We retrospectively analysed 66 patients with acute pancreatitis who underwent initial dual-contrast-phase CT (unenhanced, arterial, portal phase) at admission and short-term (mean interval 11.4 days) follow-up dual-contrast-phase dual-energy CT. The 100-kVp and linearly blended images representing 120-kVp acquisition follow-up CT images were independently evaluated by three radiologists using a modified CTSI assessing pancreatic inflammation, necrosis and extrapancreatic complications. Scores were compared with paired t test and interobserver agreement was evaluated using intraclass correlation coefficients (ICC). Results: Mean CTSI scores on unenhanced, portal- and dual-contrast-phase images were 4.9, 6.1 and 6.2 (120 kVp) and 5.0, 6.0 and 6.1 (100 kVp), respectively. Contrast-enhanced series showed a higher CTSI compared to unenhanced images (P<0.05) but no significant differences between single- and dual-contrast-phase series (P>0.7). CTSI scores were comparable for 100-kVp and 120-kVp images (P>0.05). Interobserver agreement was substantial for all evaluated series and subcategories (ICC 0.67-0.93). DLP of single-portal-phase 100-kVp images was reduced by 41 compared to 120-kVp images (363.8 versus 615.9 mGy cm). Conclusions: Low-tube-voltage single-phase 100-kVp CT provides sufficient information for follow-up evaluation of acute pancreatitis and significantly reduces radiation exposure.

Typ des Eintrags: Artikel
Erschienen: 2014
Autor(en): Wichmann, Julian L. ; Majenka, Pavel ; Beeres, Martin ; Kromen, Wolfgang ; Schulz, Boris ; Wesarg, Stefan ; Bauer, Ralf W. ; Kerl, J. Matthias ; Gruber-Rouh, Tatjana ; Hammerstingl, Renate ; Vogl, Thomas J. ; Lehnert, Thomas
Art des Eintrags: Bibliographie
Titel: Single-portal-phase Low-tube-voltage Dual-energy CT for Short-term Follow-up of Acute Pancreatitis: Evaluation of CT Severity Index, Interobserver Agreement and Radiation Dose
Sprache: Englisch
Publikationsjahr: 2014
Titel der Zeitschrift, Zeitung oder Schriftenreihe: European Radiology
Jahrgang/Volume einer Zeitschrift: 24
(Heft-)Nummer: 11
DOI: 10.1007/s00330-014-3300-0
Kurzbeschreibung (Abstract):

Objectives: To intra-individually compare single-portal-phase low-tube-voltage (100-kVp) computed tomography (CT) with 120-kVp images for short-term follow-up assessment of CT severity index (CTSI) of acute pancreatitis, interobserver agreement and radiation dose. Methods: We retrospectively analysed 66 patients with acute pancreatitis who underwent initial dual-contrast-phase CT (unenhanced, arterial, portal phase) at admission and short-term (mean interval 11.4 days) follow-up dual-contrast-phase dual-energy CT. The 100-kVp and linearly blended images representing 120-kVp acquisition follow-up CT images were independently evaluated by three radiologists using a modified CTSI assessing pancreatic inflammation, necrosis and extrapancreatic complications. Scores were compared with paired t test and interobserver agreement was evaluated using intraclass correlation coefficients (ICC). Results: Mean CTSI scores on unenhanced, portal- and dual-contrast-phase images were 4.9, 6.1 and 6.2 (120 kVp) and 5.0, 6.0 and 6.1 (100 kVp), respectively. Contrast-enhanced series showed a higher CTSI compared to unenhanced images (P<0.05) but no significant differences between single- and dual-contrast-phase series (P>0.7). CTSI scores were comparable for 100-kVp and 120-kVp images (P>0.05). Interobserver agreement was substantial for all evaluated series and subcategories (ICC 0.67-0.93). DLP of single-portal-phase 100-kVp images was reduced by 41 compared to 120-kVp images (363.8 versus 615.9 mGy cm). Conclusions: Low-tube-voltage single-phase 100-kVp CT provides sufficient information for follow-up evaluation of acute pancreatitis and significantly reduces radiation exposure.

Freie Schlagworte: Business Field: Visual decision support, Research Area: Computer vision (CV), Research Area: Human computer interaction (HCI), Computed tomography (CT), Evaluation, Monitoring
Fachbereich(e)/-gebiet(e): 20 Fachbereich Informatik
20 Fachbereich Informatik > Graphisch-Interaktive Systeme
Hinterlegungsdatum: 12 Nov 2018 11:16
Letzte Änderung: 12 Nov 2018 11:16
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